精子运动性和趋化性的激活：从无脊椎动物到人类。
Activation of motility and chemotaxis in the spermatozoa: From invertebrates to humans.
作者信息
Morisawa Masaaki, Yoshida Manabu
机构信息
Misaki Marine Biological Station, Graduate School of Science, The University of Tokyo, Miura-shi, Japan.
出版信息
Reprod Med Biol. 2005 May 3;4(2):101-114. doi: 10.1111/j.1447-0578.2005.00099.x. eCollection 2005 Jun.
Abstract
Activation of the sperm motility and chemotactic behavior of sperm toward eggs are the first communication between spermatozoa and eggs at fertilization, and understanding of the phenomena is a prerequisite for progress of not only basic biology, but also clinical aspects. The nature of molecules derived from eggs by which sperm are activated and attracted towards the eggs and the molecular mechanisms underlying the sperm activation and chemotaxis have been investigated in only a few invertebrate species, sea urchins, ascidians and herring fish. However, knowledge on this phenomena has been ignored in mammalian species including humans. The current review first introduces the studies on the activation and chemotaxis of sperm in marine invertebrates, and the same phenomena in mammals including humans, are described. (Reprod Med Biol 2005; : 101-115).
摘要
精子活力的激活以及精子向卵子的趋化行为是受精过程中精子与卵子之间的首次交流，理解这些现象不仅是基础生物学取得进展的前提，也是临床研究取得进展的前提。仅在少数几种无脊椎动物物种（海胆、海鞘和鲱鱼）中研究了卵子衍生的、激活精子并吸引精子向卵子移动的分子的性质，以及精子激活和趋化作用的分子机制。然而，包括人类在内的哺乳动物物种中，关于这一现象的知识一直被忽视。本综述首先介绍了海洋无脊椎动物中精子激活和趋化作用的研究，并描述了包括人类在内的哺乳动物中的相同现象。（《生殖医学与生物学》2005年；：101 - 115）
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