正常月经周期患者冻融胚胎移植两种不同子宫内膜准备方法的临床结局
Clinical outcomes of two different endometrial preparation methods for cryopreserved-thawed embryo transfer in patients with a normal menstrual cycle.
作者信息
Kawamura Toshihiro, Motoyama Hiroshi, Yanaihara Atsushi, Yorimitsu Takeshi, Arichi Akane, Karasawa Yasuhiro, Suga Kahori, Miya Kaoru, Ishikawa Seika, Mizushima Shiho, Kawamura Makiko
机构信息
Denentoshi Ladies' Clinic, Reproductive Medical Center, Kanagawa, Japan.
出版信息
Reprod Med Biol. 2007 Feb 16;6(1):53-57. doi: 10.1111/j.1447-0578.2007.00165.x. eCollection 2007 Mar.
Abstract
To compare the clinical outcomes of cryopreserved-thawed embryo transfer among patients with a normal menstrual cycle who had natural or hormone-replacement cycles. From January 2004 to June 2006, cryopreserved embryos following conventional fertilization (IVF) or intracytoplasmic sperm injection (ICSI) were thawed and transferred in a total of 720 natural cycles and 136 hormone-replacement cycles. Cryopreserved-thawed embryo transfer in patients who had a natural or hormone-replacement cycle resulted in clinical pregnancy in 43.1% and 40.4%, respectively; a rate of miscarriage of 14.5% and 23.6%, respectively; and a rate of ongoing pregnancy and delivery of 36.5% and 30.9%, respectively. None of these differences were statistically significant. Patients with a normal menstrual cycle who have natural or hormone-replacement cycles can be expected to have comparable clinical outcomes with cryopreserved-thawed embryo transfer. (Reprod Med Biol 2007; : 53-57).
摘要
比较自然周期或激素替代周期的月经周期正常患者冻融胚胎移植的临床结局。2004年1月至2006年6月，对常规体外受精（IVF）或卵胞浆内单精子注射（ICSI）后冻存的胚胎进行解冻，并分别在720个自然周期和136个激素替代周期中进行移植。自然周期或激素替代周期患者的冻融胚胎移植临床妊娠率分别为43.1%和40.4%；流产率分别为14.5%和23.6%；持续妊娠和分娩率分别为36.5%和30.9%。这些差异均无统计学意义。月经周期正常的患者，无论是自然周期还是激素替代周期，冻融胚胎移植的临床结局均可预期相当。（《生殖医学与生物学》2007年；：53 - 57）
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