功能性胆囊疾病真的在增多吗？罗切斯特流行病学研究项目的结果。
Is functional gallbladder disease truly increasing? Results from the Rochester Epidemiology Project.
机构信息
Department of Surgery, Mayo Clinic, 200First Street SW, Rochester, MN, 55905, USA.
出版信息
Am J Surg. 2018 Nov;216(5):932-934. doi: 10.1016/j.amjsurg.2018.04.001. Epub 2018 Apr 17.
INTRODUCTION
Reports from US administrative databases showed an increase in cholecystectomy rate for functional gallbladder disorder (FGBD), a disease is not well recognized elsewhere. We aimed to identify the incidence and cholecystectomy rate for FGBD in an epidemiologically well-defined and prospectively studied population and compare results to published data.
METHODS
After IRB approval, we extracted data from the NIH funded Rochester Epidemiology Project. We used ICD-9 codes (575.8) and (575.9) to identify patients with FGBD from 2000 to 2014.
RESULTS
Between 2000 and 2014 we identified 253 patients with specified ICD-9 codes and no stones among a population of 135,000. Based on their medical records, 24 patients had confirmed FGBD, the incidence was 1.77/10,000 and cholecystectomy rate was for these patients was 70%.
CONCLUSION
The incidence of FGBD was much lower than State data with similar cholecystectomy rate. Additional investigation may be needed to understand if cholecystectomy rate is truly increasing.
简介
来自美国行政数据库的报告显示，功能性胆囊疾病（FGBD）的胆囊切除术率有所增加，而这种疾病在其他地方并未得到很好的认识。我们旨在确定在一个具有明确流行病学特征且进行前瞻性研究的人群中 FGBD 的发病率和胆囊切除术率，并将结果与已发表的数据进行比较。
方法
在获得机构审查委员会批准后，我们从美国国立卫生研究院资助的罗切斯特流行病学项目中提取数据。我们使用 ICD-9 编码（575.8）和（575.9）从 2000 年至 2014 年确定 FGBD 患者。
结果
在 2000 年至 2014 年期间，我们在 135000 名人群中发现了 253 名具有特定 ICD-9 编码且无结石的患者。根据他们的病历，有 24 名患者被确诊为 FGBD，发病率为 1.77/10000，这些患者的胆囊切除术率为 70%。
结论
FGBD 的发病率远低于具有相似胆囊切除术率的州数据。可能需要进一步调查以了解胆囊切除术率是否真的在增加。
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