Guo Jun
Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Chin J Integr Med. 2018 Jul;24(7):483-486. doi: 10.1007/s11655-018-2555-8. Epub 2018 Apr 25.
Oligo-astheno-teratozoospermia (OAT) which perplexes doctors and patients due to its complicated etiology, atypical symptoms and poor clinical efficacy, is a general term for the three pathological states of abnormal semen. OAT is the main factor of male infertility. It is also a hot and difficult point in present studies. Empiric drug is the most popular treatment of this disease in the modern medicine. Chinese medicine (CM) is one of the main methods for the treatment of this disease, and it has certain clinical effect. The author believes that the use of modern medical technology to make the diagnosis as clear as possible is the key to treat OAT. The combination of syndrome and disease differentiation is the main mode in the treatment of OAT. Microscopic syndrome differentiation and macroscopic evidence embodies the basic principle of "Si Wai Chuai Nei" and broadens the perspective of CM syndrome differentiation. Classification and treatment are basic methods for the treatment of OAT. The treatment should not be limited to the Shen (Kidney), instead it should focus on the whole body condition. At different stages, the treatment should also pay attention to strengthening the Pi (Spleen), nourishing the Gan (Liver) and promoting blood circulation. Complementing Chinese and Western medicine, and highlighting the characteristics and advantages of CM treatment, have a great guiding value for the treatment of OAT.
少弱畸精子症（OAT）因其病因复杂、症状不典型、临床疗效不佳而困扰着医生和患者，是精液异常三种病理状态的统称。OAT是男性不育的主要因素，也是目前研究的热点和难点。经验性用药是现代医学中治疗该病最常用的方法。中医是治疗该病的主要方法之一，且具有一定的临床疗效。笔者认为，运用现代医学技术尽可能明确诊断是治疗OAT的关键。辨证与辨病相结合是治疗OAT的主要模式。微观辨证与宏观证据体现了“司外揣内”的基本原理，拓宽了中医辨证的视野。分型论治是治疗OAT的基本方法。治疗不应局限于肾，而应着眼于全身状况。在不同阶段，治疗还应注重健脾、养肝和活血化瘀。中西医互补，突出中医治疗的特色与优势，对OAT的治疗具有重要的指导价值。
