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[持续性非卧床腹膜透析期间腹膜炎的预防。可断开连接系统的价值]

[Prevention of peritonitis during continuous ambulatory peritoneal dialysis. Value of disconnectable systems].

作者信息

Rottembourg J, Brouard R, Issad B, Allouache M, Nguyen J, Montassine M C, Kirstein E, Jacobs C

机构信息

Service de Néphrologie, Groupe Hospitalier Pitié-Salpêtrière.

出版信息

Presse Med. 1988 Jul 2;17(26):1349-53.

PMID:2970080
Abstract

Peritonitis remains the major obstacle to the acceptance of continuous ambulatory peritoneal dialysis as a long-term dialysis technique. In January, 1985, Y connectors were introduced into our continuous ambulatory peritoneal dialysis programme, and a two-year prospective randomized trial for all new patients was initiated in which the Y connection system was compared with the conventional technique in the prevention of peritonitis (group I). At the same time, 16 patients (group II), with a high incidence of peritonitis episodes were switched from the conventional technique to the Y connection system, while 55 patients (group III), remained on the conventional technique. Group IA patients (27 new patients using the Y connection system), developed peritonitis every 23 patient-months. Group IB patients (28 new patients using the conventional technique), developed peritonitis every 12.2 patient-months. The difference between these two sub-groups was statistically significant (P less than 0.02). Before their transfer to the Y connection system, group II patients developed peritonitis every 10 patient-months and thereafter one every 24 patient-months (P less than 0.001). Group III patients were divided into 12 continuous cyclic peritoneal dialysis patients with peritonitis every 24 patients-months, and 43 continuous ambulatory peritoneal dialysis patients with peritonitis every 11.7 patient-months. The Y connector therefore proved to be a simple and safe procedure effective in reducing the peritonitis rate in patients on continuous ambulatory peritoneal dialysis.

摘要

腹膜炎仍然是持续性非卧床腹膜透析作为一种长期透析技术被广泛接受的主要障碍。1985年1月,Y形连接器被引入我们的持续性非卧床腹膜透析项目,并对所有新患者启动了一项为期两年的前瞻性随机试验,在该试验中,将Y形连接系统与传统技术在预防腹膜炎方面进行比较(第一组)。同时,16例腹膜炎发作发生率高的患者(第二组)从传统技术转换为Y形连接系统,而55例患者(第三组)继续采用传统技术。第一组A患者(27例使用Y形连接系统的新患者)每23个患者月发生一次腹膜炎。第一组B患者(28例使用传统技术的新患者)每12.2个患者月发生一次腹膜炎。这两个亚组之间的差异具有统计学意义(P小于0.02)。在转用Y形连接系统之前,第二组患者每10个患者月发生一次腹膜炎,之后每24个患者月发生一次(P小于0.001)。第三组患者分为12例持续性循环腹膜透析患者,每24个患者月发生一次腹膜炎,以及43例持续性非卧床腹膜透析患者,每11.7个患者月发生一次腹膜炎。因此,Y形连接器被证明是一种简单安全的方法,可有效降低持续性非卧床腹膜透析患者的腹膜炎发生率。

相似文献

1
[Prevention of peritonitis during continuous ambulatory peritoneal dialysis. Value of disconnectable systems].[持续性非卧床腹膜透析期间腹膜炎的预防。可断开连接系统的价值]
Presse Med. 1988 Jul 2;17(26):1349-53.
2
Clinical efficacy and morbidity associated with continuous cyclic compared with continuous ambulatory peritoneal dialysis.持续循环腹膜透析与持续非卧床腹膜透析相比的临床疗效及发病率
Ann Intern Med. 1994 Feb 15;120(4):264-71. doi: 10.7326/0003-4819-120-4-199402150-00002.
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Prospective controlled trial of a Y-connector and disinfectant to prevent peritonitis in continuous ambulatory peritoneal dialysis.
Lancet. 1983 Sep 17;2(8351):642-4. doi: 10.1016/s0140-6736(83)92528-x.
4
A prospective, randomized study comparing the peritonitis incidence of CAPD and Y-connector (CAPD-Y) with continuous cyclic peritoneal dialysis (CCPD).一项前瞻性随机研究,比较持续性非卧床腹膜透析(CAPD)和Y型连接管持续性非卧床腹膜透析(CAPD-Y)与持续循环腹膜透析(CCPD)的腹膜炎发生率。
Adv Perit Dial. 1991;7:186-9.
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Fivefold reduction in peritonitis using a multifaceted continuous quality initiative program.通过多方面持续质量改进计划,腹膜炎发生率降低了五倍。
Adv Perit Dial. 2003;19:202-5.
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Peritonitis prevented in continuous ambulatory peritoneal dialysis by using the Hong Kong connection.采用香港连接法预防持续性非卧床腹膜透析中的腹膜炎。
Br Med J (Clin Res Ed). 1984 Feb 4;288(6414):353-6. doi: 10.1136/bmj.288.6414.353.
7
Low incidence of peritonitis with the T-set.T型装置导致腹膜炎的发生率较低。
Adv Perit Dial. 1994;10:147-9.
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Improved training techniques and UltraBag system resulted in lowered peritonitis rate in an inner-city population.
Adv Perit Dial. 1995;11:208-9.
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[Peritoneal complications of continuous ambulatory peritoneal dialysis].[持续性非卧床腹膜透析的腹膜并发症]
Minerva Urol Nefrol. 1992 Jan-Mar;44(1):57-61.
10
Peritonitis in continuous ambulatory peritoneal dialysis (CAPD): a multi-centre randomized clinical trial comparing the Y connector disinfectant system to standard systems. Canadian CAPD Clinical Trials Group.持续性非卧床腹膜透析(CAPD)中的腹膜炎:一项比较Y型接头消毒系统与标准系统的多中心随机临床试验。加拿大CAPD临床试验组。
Perit Dial Int. 1989;9(3):159-63.

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