丁型肝炎：堪萨斯城发现的首例两例病例。

Delta hepatitis: first two cases identified in Kansas City.

作者信息

Schnell G A, Schubert T T

机构信息

Department of Gastroenterology, University of Missouri-Kansas City.

出版信息

South Med J. 1988 Aug;81(8):952-5. doi: 10.1097/00007611-198808000-00004.

DOI:10.1097/00007611-198808000-00004

PMID:2970116

Abstract

Hepatitis delta virus (HDV) was identified in 1977 and has since been found to be a worldwide disease. Prevalence in North America is highest among drug abusers. We present two IV drug abusers from the city hospital in Kansas City as the first two cases identified in the city, one with apparent superinfection and the other with a chronic HDV infection. We review the various manifestations and diagnosis of HDV, and advocate prevention of spread of HDV infection by hepatitis B vaccination and use of single donor blood products in high-risk patients.

摘要

丁型肝炎病毒（HDV）于1977年被发现，自那时起已被认定为一种全球性疾病。在北美，药物滥用者中的患病率最高。我们报告了堪萨斯城城市医院的两名静脉注射药物滥用者，他们是该市确诊的首例和第二例病例，其中一例为明显的重叠感染，另一例为慢性HDV感染。我们回顾了HDV的各种表现和诊断方法，并提倡通过接种乙肝疫苗和在高危患者中使用单供血者血液制品来预防HDV感染的传播。