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墨尔本15年间丁型肝炎病毒(δ病毒)感染的流行病学情况。

Epidemiology of hepatitis D virus (delta) infection in Melbourne over a 15-year period.

作者信息

Dimitrakakis M, Waters M J, Wootton A L, Gust I D

出版信息

Med J Aust. 1986;145(3-4):128-30. doi: 10.5694/j.1326-5377.1986.tb113769.x.

DOI:10.5694/j.1326-5377.1986.tb113769.x
PMID:3736476
Abstract

The prevalence of delta infection was studied in 3986 individuals seropositive for hepatitis B surface antigen (HBsAg), who were seen in Melbourne between 1971 and 1985. The group comprised 2004 patients with acute hepatitis B, 1820 asymptomatic HBsAg carriers, 139 HBsAg carriers with evidence of chronic liver disease, and 23 carriers who had suffered more than two separate attacks of acute hepatitis. Markers of delta infection were found almost exclusively among intravenous drug abusers and their close contacts. Studies of stored sera suggest that delta infection was introduced into this group about 1970. In carriers with no evidence of chronic liver disease, the prevalence of delta infection was highest among intravenous drug abusers (19.2%). In carriers with evidence of chronic liver disease, delta markers were present in 20.1% and all 23 carriers with recurrent acute hepatitis had evidence of infection with the delta virus.

摘要

对1971年至1985年间在墨尔本就诊的3986名乙肝表面抗原(HBsAg)血清学阳性个体的丁型感染患病率进行了研究。该组包括2004例急性乙型肝炎患者、1820例无症状HBsAg携带者、139例有慢性肝病证据的HBsAg携带者以及23例曾遭受两次以上急性肝炎发作的携带者。丁型感染标志物几乎仅在静脉注射吸毒者及其密切接触者中发现。对储存血清的研究表明,丁型感染于1970年左右传入该组。在无慢性肝病证据的携带者中,静脉注射吸毒者的丁型感染患病率最高(19.2%)。在有慢性肝病证据的携带者中,20.1%存在丁型标志物,所有23例复发性急性肝炎携带者均有丁型病毒感染的证据。

相似文献

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Epidemiology of hepatitis D virus (delta) infection in Melbourne over a 15-year period.墨尔本15年间丁型肝炎病毒(δ病毒)感染的流行病学情况。
Med J Aust. 1986;145(3-4):128-30. doi: 10.5694/j.1326-5377.1986.tb113769.x.
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Hepatitis B and D virus infection among drug abusers in Taiwan.台湾地区药物滥用者中的乙型和丁型肝炎病毒感染
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Current seroepidemiology of hepatitis D virus infection among hepatitis B surface antigen carriers of general and high-risk populations in Taiwan.台湾一般人群和高危人群乙肝表面抗原携带者中丁型肝炎病毒感染的当前血清流行病学情况。
J Med Virol. 1992 Oct;38(2):97-101. doi: 10.1002/jmv.1890380205.

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World J Gastroenterol. 2010 Feb 7;16(5):554-62. doi: 10.3748/wjg.v16.i5.554.