心肌梗死患者静脉注射链激酶后延迟进行经皮腔内冠状动脉成形术的疗效。
Efficacy of delayed percutaneous transluminal coronary angioplasty after intravenous use of streptokinase in myocardial infarction.
作者信息
Gagnon R M, Morissette M, Laramée P, Dumont G, Sestier F, Leclerc G, Goudreau E
机构信息
Department of Medicine, University of Montreal, Notre-Dame Hospital.
出版信息
CMAJ. 1988 Sep 1;139(5):405-8.
Between June 1984 and December 1986, 35 patients with acute myocardial infarction received streptokinase intravenously within 3 hours after the beginning of chest pain and underwent percutaneous transluminal coronary angioplasty (PTCA) either immediately (in 2 cases) or 1 to 19 (mean 4.4) days later (in 33). The rate of successful PTCA was 89%. Reocclusion occurred in one patient. The mean percentage of stenosis decreased from 86% to 11%. The mean trans-stenotic gradient was reduced from 41 to 11 mm Hg. The results suggest that in patients whose condition is stable, PTCA performed a few days after thrombolysis is a valuable alternative to more aggressive treatment with immediate PTCA.
1984年6月至1986年12月期间，35例急性心肌梗死患者在胸痛发作后3小时内静脉注射链激酶，并于胸痛发作后即刻（2例）或1至19天（平均4.4天）后（33例）接受经皮腔内冠状动脉成形术（PTCA）。PTCA成功率为89%。1例患者发生再闭塞。狭窄平均百分比从86%降至11%。平均跨狭窄压差从41 mmHg降至11 mmHg。结果表明，对于病情稳定的患者，溶栓治疗几天后进行PTCA是比立即进行PTCA等更积极治疗更有价值的替代方案。
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