Mehta A B, Abhyankar A D
L.T.M.G. Hospital & L.T.M. Medical College, Sion, Bombay.
J Assoc Physicians India. 1994 Jan;42(1):43-4.
Reperfusion in acute myocardial Infarction [AMI] can be realised by thrombolytic therapy or percutaneous transluminal coronary angioplasty [PTCA] has theoretical advantage but hardly any randomised trials have been published till recently to compare the two modalities. We started the STAT trial with this objective. Patients of AMI were randomised to thrombolytic therapy or PTCA. In the present article we present the phase I data of the PTCA limb. The procedural success rate was 100% with no procedural mortality. In-hospital mortality was 10% [Anterior Infarction 0%, Inferior infarction 20%]. Recurrence of angina occurred in 10% patients. Direct PTCA to left anterior descending artery appeared to be more rewarding than PTCA to right coronary artery.
急性心肌梗死(AMI)的再灌注可通过溶栓治疗或经皮腔内冠状动脉成形术(PTCA)来实现,PTCA具有理论优势,但直到最近几乎没有发表过比较这两种方式的随机试验。我们带着这个目标启动了STAT试验。将AMI患者随机分为溶栓治疗组或PTCA组。在本文中,我们展示了PTCA组的I期数据。手术成功率为100%,无手术死亡病例。住院死亡率为10%(前壁梗死0%,下壁梗死20%)。10%的患者出现心绞痛复发。直接对左前降支进行PTCA似乎比右冠状动脉PTCA更有成效。