National Drug and Alcohol Research Centre, University of New South Wales, Australia; NHMRC Centre for Research Excellence in Mental Health and Substances Use, University of New South Wales, Australia.
National Drug and Alcohol Research Centre, University of New South Wales, Australia; NHMRC Centre for Research Excellence in Mental Health and Substances Use, University of New South Wales, Australia.
J Subst Abuse Treat. 2018 Jun;89:60-66. doi: 10.1016/j.jsat.2018.04.001. Epub 2018 Apr 4.
The high prevalence of post traumatic stress disorder (PTSD) among people with heroin dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown. This paper examines the impact of current and lifetime PTSD on long-term recovery from heroin dependence among participants who took part in the 11-year follow-up of the Australian Treatment Outcome Study (ATOS), a prospective naturalistic longitudinal study of 615 people with heroin dependence recruited from Sydney, Australia, in 2001-2002. Seventy-one percent of the cohort (n = 431) were re-interviewed 11-years post study entry. Outcomes examined included heroin and other drug use, dependence, general physical and mental health, depression, PTSD, employment, and the incidence of trauma exposure, overdose, imprisonment, and attempted suicide over the 11- year follow-up. Despite having a poorer profile at baseline, individuals with current PTSD or a history of PTSD at baseline demonstrated similar levels of improvement to those without a history of PTSD in all outcome domains across the 11-year follow-up, PTSD was associated with consistently higher levels of major depression, and attempted suicide, subsequent trauma exposure, and poorer occupational functioning across the 11-year follow-up. These findings highlight the importance of interventions aimed at occupational rehabilitation, reducing the likelihood of retraumatisation, and addressing PTSD and associated comorbidities among people with heroin dependence.
创伤后应激障碍(PTSD)在海洛因依赖者中高发,且对短期结局有影响,这一点已得到充分证实。然而,PTSD 对长期康复的影响尚不清楚。本文考察了澳大利亚治疗结局研究(ATOS)11 年随访中参与者的当前和终生 PTSD 对海洛因依赖长期康复的影响。ATOS 是一项前瞻性自然主义纵向研究,2001-2002 年在澳大利亚悉尼招募了 615 名海洛因依赖者。71%(n=431)的队列在研究入组后 11 年接受了重新访谈。考察的结局包括海洛因和其他药物使用、依赖、一般身体和心理健康、抑郁、PTSD、就业以及创伤暴露、过量用药、监禁和自杀未遂的发生率,随访时间为 11 年。尽管基线时的情况较差,但与没有 PTSD 病史的个体相比,当前患有 PTSD 或有 PTSD 病史的个体在所有结局领域中,在 11 年的随访期间,其改善水平相似,PTSD 与更高水平的重度抑郁、自杀未遂、随后的创伤暴露和较差的职业功能相关,在 11 年的随访期间一直如此。这些发现强调了针对职业康复、减少再创伤可能性以及解决海洛因依赖者 PTSD 及相关合并症的干预措施的重要性。