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冠心病监护病房中患者管理的机械循环辅助

Mechanical circulatory assistance in the management of patients in coronary care unit.

作者信息

Szatmáry L J, Bernadet P, Puel P

机构信息

Department of Coronary Care Unit, University Hospital Toulouse Purpan, France.

出版信息

Acta Med Hung. 1988;45(1):9-21.

PMID:2970622
Abstract

Mechanical circulatory assistance was attempted in 73 patients at our coronary care unit from January 1, 1983, to January 1, 1987. Of these, 62 were men and 11 were women. The intra-aortic balloon pump (IABP) was successfully inserted by percutaneous femoral puncture in all cases. Indications for an IABP included: acute infarction and haemodynamic deterioration (23 cases), refractory congestive heart failure (2 cases), hypotension, ST-T changes and chest pain complicating coronarography or coronary angioplasty procedures (16 cases), unstable angina pectoris resistent to medical therapy, treated by coronary angioplasty (16 cases) and preoperative haemodynamic coverage (16 cases). The overall major complication rate of IABP was 1.5%. Our experience supports aggressive management of cardiogenic shock, i.e. early angioplasty or cardiac surgery, which considerably influences the functional status and the long-term survival rate (7/9 cases) over medical therapy combined with IABP (2 of the 14 patients are alive). The IABP was also effective in managing other high-risk patients when it was combined with some form of definitive cardioprotective mechanical correction, i.e. aneurysmectomy, valve replacement, coronary recanalization procedure. When the counterpulsation was used prophylactically, no interventional myocardial infarctions or deaths occurred; the survival rate was 27/32 patients for a 22 month average follow-up. It is suggested that the clinical results and late survival were improved by use of IABP in selected patients undergoing coronary angioplasty or open-heart surgery.

摘要

1983年1月1日至1987年1月1日期间,我们冠心病监护病房对73例患者尝试了机械循环辅助。其中,男性62例,女性11例。所有病例均通过经皮股动脉穿刺成功插入主动脉内球囊泵(IABP)。IABP的适应证包括:急性梗死和血流动力学恶化(23例)、难治性充血性心力衰竭(2例)、低血压、ST-T改变以及冠状动脉造影或冠状动脉成形术过程中出现的胸痛(16例)、药物治疗无效的不稳定型心绞痛,经冠状动脉成形术治疗(16例)和术前血流动力学支持(16例)。IABP的总体主要并发症发生率为1.5%。我们的经验支持对心源性休克进行积极治疗,即早期进行血管成形术或心脏手术,这对功能状态和长期生存率(9例中的7例)的影响远大于药物治疗联合IABP(14例患者中有2例存活)。当IABP与某种形式的确定性心脏保护机械矫正措施(如动脉瘤切除术、瓣膜置换术、冠状动脉再通术)联合使用时,对其他高危患者也有效。当预防性使用反搏时,未发生介入性心肌梗死或死亡;平均随访22个月,32例患者中有27例存活。建议在接受冠状动脉成形术或心脏直视手术的特定患者中使用IABP可改善临床结果和晚期生存率。

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