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[难治性不稳定型心绞痛。主动脉反搏下冠状动脉血管成形术的急诊治疗]

[Refractory unstable angina. Emergency treatment by coronary artery angioplasty under aortic counterpulsion].

作者信息

Chague F, Colle J P, Delarche N, Ohayon J, Besse P

机构信息

Hôpital Cardiologique, INSERM U8, Université de Bordeaux II, Pessac.

出版信息

Arch Mal Coeur Vaiss. 1987 Nov;80(12):1745-51.

PMID:2965560
Abstract

We report our experience of 15 transluminal coronary angioplasties performed in an emergency in 13 patients (mean age 67 +/- 8 years) with refractory unstable angina. The procedures were conducted under diastolic counterpulsation effected by means of an intra-aortic balloon. The angina was of the threatening infarction type on 11 occasions and of the threatening extended infarction on 4 occasions. Electrocardiographic abnormalities were recorded in the anterior (11 cases) or in the inferior (4 cases) territory. Three patients had a very alarming haemodynamic status, with acute pulmonary oedema in two and cardiogenic shock in one. After intra-aortic counterpulsation was installed and the clinical signs were stabilized, coronaro-ventriculography was performed, leading to a decision of immediate angioplasty since age, underlying diseases, myocardial function and diffused lesions made most of the patients unsuitable for surgery. In multiple vessel patients electric and angiographic data were used to locate the tight stenosis (92% in all cases) responsible for the acute coronary ischaemia. The stenosis was found to affect the anterior interventricular artery in 9 cases, the circumflex artery in 2 cases, the right coronary artery in 2 cases and a saphenous shunt on the anterior interventricular artery in 2 cases. Immediate arteriographic and clinical success was obtained in 12 out of 15 cases (80%); there were 3 failures with 2 transmural infarctions. Later on, 2 patients underwent aorto-coronary bypass and 1 died of myocardial failure and pulmonary superinfection 3 weeks after the procedure. Ten of our 13 patients were stabilized and were discharged under medical treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们报告了对13例(平均年龄67±8岁)难治性不稳定型心绞痛患者进行15次急诊经腔冠状动脉血管成形术的经验。手术在主动脉内球囊产生的舒张期反搏下进行。11次发作时心绞痛为梗死先兆型,4次发作时为梗死扩展先兆型。心电图异常记录于前壁(11例)或下壁(4例)区域。3例患者血流动力学状态极不稳定,2例出现急性肺水肿,1例出现心源性休克。在安装主动脉内反搏且临床症状稳定后,进行了冠状动脉心室造影,鉴于年龄、基础疾病、心肌功能及弥漫性病变使大多数患者不适合手术,因此决定立即进行血管成形术。对于多支血管病变患者,利用电生理和血管造影数据定位导致急性冠状动脉缺血的严重狭窄(所有病例中均为92%)。发现9例狭窄累及前室间动脉,2例累及旋支动脉,2例累及右冠状动脉,2例累及前室间动脉的大隐静脉分流。15例中有12例(80%)即刻获得血管造影和临床成功;3例失败,其中2例发生透壁性梗死。后来,2例患者接受了主动脉冠状动脉搭桥术,1例在术后3周死于心肌衰竭和肺部感染。我们的13例患者中有10例病情稳定,经药物治疗后出院。(摘要截取自250字)

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