International Emerging Infections Program, Division of Global Health Protection, Center for Global Health, U.S. Centers for Disease Control and Prevention, Beijing, China.
Chinese Center for Health Education, Beijing, China.
Vaccine. 2018 May 31;36(23):3315-3322. doi: 10.1016/j.vaccine.2018.04.060. Epub 2018 Apr 26.
Pregnant women are at higher risk for complications from influenza infection. Nevertheless, seasonal influenza vaccination among pregnant women in China is low. A better understanding of perceptions of pregnant women and their physicians, and factors influencing decisions about receiving seasonal influenza vaccine could be used to develop effective strategies for improving seasonal influenza vaccine uptake during pregnancy.
We recruited pregnant women from 9 hospitals located in 5 cities across China to participate in focus group interviews. Obstetricians from the same hospitals were recruited for one on one in-depth interviews. We collected information about perceptions of barriers and motivating factors for utilizing seasonal influenza vaccine during pregnancy. We systematically analyzed the information using qualitative methods.
We conducted 18 focus groups with 108 pregnant women and interviewed 18 obstetricians. Awareness about the use of influenza vaccine during pregnancy was minimal in both subject groups. None of the pregnant women had received influenza vaccine during pregnancy and none of the obstetricians had recommended influenza vaccine for their patients. Both groups noted insufficient knowledge about influenza infection and benefits of the vaccine, concerns about vaccine safety, and lack of local data related to vaccine use in Chinese pregnant women. Obstetricians cited the lack of a national policy as a major barrier to recommending seasonal influenza vaccine to pregnant women. Pregnant women cited not receiving a recommendation for vaccination from healthcare workers as an additional barrier.
Our findings highlight the immediate need to increase awareness and knowledge about the risks of influenza infection and the benefits and safety of seasonal influenza vaccination among both pregnant women and obstetricians in China. Obstetricians interviewed stated that the development and implementation of a national policy prioritizing pregnant women for seasonal influenza vaccination would facilitate their willingness to recommend seasonal influenza vaccine to pregnant women.
孕妇感染流感后出现并发症的风险更高。然而,中国孕妇接种季节性流感疫苗的比例较低。更好地了解孕妇及其医生的看法,以及影响他们决定接种季节性流感疫苗的因素,可用于制定有效策略,提高孕妇在孕期接种季节性流感疫苗的比例。
我们从中国 5 个城市的 9 家医院招募了孕妇参加焦点小组访谈。来自同一医院的妇产科医生则接受了一对一的深入访谈。我们收集了有关在孕期使用季节性流感疫苗的看法、障碍和促进因素的信息。我们使用定性方法系统地分析了这些信息。
我们共进行了 18 次焦点小组访谈,共有 108 名孕妇参加,还对 18 名妇产科医生进行了访谈。两组对象对孕期使用流感疫苗的认识都很有限。孕妇中没有一人在孕期接种过流感疫苗,妇产科医生也没有向患者推荐过流感疫苗。两组均表示对流感感染和疫苗益处的了解不足,对疫苗安全性的担忧,以及缺乏与中国孕妇疫苗使用相关的本地数据。妇产科医生提到缺乏国家政策是向孕妇推荐季节性流感疫苗的主要障碍。孕妇提到没有从医护人员那里得到接种疫苗的建议,这也是一个额外的障碍。
我们的研究结果突出表明,中国孕妇和妇产科医生急需提高对流感感染风险、季节性流感疫苗益处和安全性的认识和了解。接受访谈的妇产科医生表示,制定和实施一项优先为孕妇接种季节性流感疫苗的国家政策,将有助于他们愿意向孕妇推荐季节性流感疫苗。