一种用于测量移植的颌面游离皮瓣血管灌注的紧凑型仪器。
A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps.
作者信息
Kolodziejski Noah J, Stapels Christopher J, McAdams Daniel R, Fernandez Daniel E, Podolsky Matthew J, Farkas Dana, Ward Brent B, Vartarian Mark, Feinberg Stephen E, Lee Seung Yup, Parikh Urmi, Mycek Mary-Ann, Christian James F
机构信息
Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA.
Northeastern Univ., Boston, MA USA.
出版信息
Proc SPIE Int Soc Opt Eng. 2016 Feb;9715. doi: 10.1117/12.2212872. Epub 2016 Mar 4.
Abstract
The vascularization and resulting perfusion of transferred tissues are critical to the success of grafts in buried free flap transplantations. To enable long-term clinical monitoring of grafted tissue perfusion during neovascularization and endothelialization, we are developing an implantable instrument for the continuous monitoring of perfusion using diffuse correlation spectroscopy (DCS), and augmented with diffuse reflectance spectroscopy (DRS). This work discusses instrument construction, integration, and preliminary results using a porcine graft model.
摘要
在带蒂游离皮瓣移植中，移植组织的血管化及由此产生的灌注对移植成功至关重要。为了在新生血管形成和内皮化过程中对移植组织灌注进行长期临床监测，我们正在开发一种可植入仪器，利用扩散相关光谱法（DCS）并结合漫反射光谱法（DRS）对灌注进行连续监测。本文讨论了使用猪移植模型的仪器构建、集成及初步结果。
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