Hutchison K J, Karpinski E
Department of Physiology, University of Alberta, Edmonton, Canada.
Ultrasound Med Biol. 1988;14(4):269-75. doi: 10.1016/0301-5629(88)90092-0.
Pulsed Doppler velocimetry was used to construct velocity profiles which demonstrated jet flow and recirculation in the poststenotic velocity field of canine peripheral arteries in vivo. Maximal spectral broadening in near midline velocity waveforms was used to assess turbulent type flow disturbance. A doubling or halving of mean volume flow, in iliac and carotid arteries, respectively, had no effect on the spatial relationship of these flow patterns. Peak jet velocity was changed less, and end diastolic velocity was changed more than expected. Magnitude of turbulent type flow disturbance was reduced by halving but not doubling flow. Effects of changes in pulsatility and heart rate are discussed. It is suggested that similar variation in maximum and end diastolic jet velocities and poststenotic spectral broadening will occur in patients undergoing noninvasive diagnostic tests for arterial disease. This will reduce the resolution of methods based on absolute levels of these parameters.
采用脉冲多普勒测速法构建速度剖面，结果显示在体犬外周动脉狭窄后速度场存在射流和再循环。利用近中线速度波形中的最大频谱展宽来评估湍流型血流紊乱。分别使髂动脉和颈动脉的平均容积流量加倍或减半，对这些血流模式的空间关系没有影响。射流峰值速度变化较小，而舒张末期速度变化比预期的大。将流量减半可降低湍流型血流紊乱的程度，但流量加倍则无此效果。文中讨论了搏动性和心率变化的影响。研究表明，在接受动脉疾病无创诊断检查的患者中，最大和舒张末期射流速度以及狭窄后频谱展宽会出现类似变化。这将降低基于这些参数绝对水平的方法的分辨率。
