利用脱细胞真皮基质修复腭裂瘘管
Cleft Palate Fistula Closure Utilizing Acellular Dermal Matrix.
作者信息
Emodi Omri, Ginini Jiriys George, van Aalst John A, Shilo Dekel, Naddaf Raja, Aizenbud Dror, Rachmiel Adi
机构信息
Department of Oral and Maxillofacial Surgery, Rambam Health Care Campus, Haifa, Israel; Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel; Division of Pediatric Plastic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and Department of Orthodontics, Rambam Health Care Campus, Haifa, Israel.
出版信息
Plast Reconstr Surg Glob Open. 2018 Mar 13;6(3):e1682. doi: 10.1097/GOX.0000000000001682. eCollection 2018 Mar.
Fistulas represent failure of cleft palate repair. Secondary and tertiary fistula repair is challenging, with high recurrence rates. In the present retrospective study, we review the efficacy of using acellular dermal matrix as an interposition layer for cleft palate fistula closure in 20 consecutive patients between 2013 and 2016. Complete fistula closure was obtained in 16 patients; 1 patient had asymptomatic recurrent fistula; 2 patients had partial closure with reduction of fistula size and minimal nasal regurgitation; 1 patient developed a recurrent fistula without changes in symptoms (success rate of 85%). We conclude that utilizing acellular dermal matrix for cleft palate fistula repair is safe and simple with a high success rate.
腭裂瘘代表腭裂修复失败。二期和三期腭裂瘘修复具有挑战性，复发率高。在本回顾性研究中，我们回顾了2013年至2016年间连续20例患者使用脱细胞真皮基质作为腭裂瘘闭合的插入层的疗效。16例患者实现了瘘管完全闭合；1例患者有无症状复发性瘘管；2例患者部分闭合，瘘管尺寸减小，鼻反流最小；1例患者出现复发性瘘管，但症状无变化（成功率为85%）。我们得出结论，使用脱细胞真皮基质进行腭裂瘘修复安全、简单，成功率高。
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