Majumder Parthopratim Dutta, Sitaula Ranju Kharel, Biswas Jyotirmay
J Pediatr Ophthalmol Strabismus. 2018 Jul 1;55(4):270-274. doi: 10.3928/01913913-20180213-01. Epub 2018 May 1.
To report the clinical profiles, etiologies, treatment modalities, and outcomes for Eales disease in patients younger than age 16 years in India.
Retrospective review of medical records of patients with Eales disease who had a minimum 5-year follow-up period.
A total of 25 eyes of 13 patients were included. Of these 13 patients, 12 (94%) had bilateral Eales disease and 11 (84.6%) were men. Mean patient age was 14.1 years (range: 11 to 16 years). Diminution of vision (36%) was the most common presenting complaint, followed by both diminutions of vision and floaters (32%). Sclerosed vessels were seen in all eyes, and 21 (84%) eyes had active periphlebitis at presentation. Neovascularization elsewhere was seen in 20 (80%) eyes and neovascularization of the optic disc was seen in 1 (4%) eye. Veno-venous shunts were found in 12 (48%) eyes, and 18 (72%) eyes had vitreous hemorrhage. All eyes received photocoagulation; 84.6% of patients received oral steroids, with 7.7% of patients treated with azathioprine and 38.4% treated with anti-tubercular therapy. Vitrectomy was performed in 36% of eyes for non-clearing vitreous hemorrhage and tractional retinal detachment. Vision improved in 7 (28%) eyes, was stable in 12 (48%) eyes, and worsened in 6 (24%) eyes. Recurrence of the disease more than five times during the 5-year follow-up period occurred in 20% of patients.
Recurrent vasculitis and vitreous hemorrhage in children should raise the suspicion of pediatric Eales disease. [J Pediatr Ophthalmol Strabismus. 2018;55(4):270-274.].
报告印度16岁以下伊尔斯病患者的临床特征、病因、治疗方式及治疗结果。
对至少随访5年的伊尔斯病患者的病历进行回顾性分析。
共纳入13例患者的25只眼。这13例患者中，12例（94%）患有双侧伊尔斯病，11例（84.6%）为男性。患者平均年龄为14.1岁（范围：11至16岁）。视力下降（36%）是最常见的就诊主诉，其次是视力下降和飞蚊症（32%）。所有眼中均可见硬化血管，21只眼（84%）在就诊时存在活动性周边静脉炎。20只眼（80%）可见其他部位新生血管形成，1只眼（4%）可见视盘新生血管形成。12只眼（48%）发现静脉-静脉分流，18只眼（72%）发生玻璃体积血。所有眼均接受了光凝治疗；84.6%的患者接受了口服类固醇治疗，7.7%的患者接受硫唑嘌呤治疗，38.4%的患者接受抗结核治疗。36%的眼因玻璃体积血不吸收和牵拉性视网膜脱离接受了玻璃体切除术。7只眼（28%）视力改善，12只眼（48%）视力稳定，6只眼（24%）视力恶化。20%的患者在5年随访期内疾病复发超过5次。
儿童反复出现的血管炎和玻璃体积血应怀疑小儿伊尔斯病。[《小儿眼科与斜视杂志》。2018；55(4)：270 - 274。]
