a Medical and Vision Research Foundations, Sankara Nethralaya, Uvea and Ocular Pathology , Chennai , Tamil Nadu , India.
b Little Flower Hospital , Angamaly Ernakulam Kerala , India.
Ocul Immunol Inflamm. 2018;26(6):870-876. doi: 10.1080/09273948.2017.1298817. Epub 2017 Apr 27.
To analyze the long-term visual outcomes of Eales' patients.
A retrospective review of Eales' patients diagnosed between 1985 and 1995 with >10 years follow-up done.
We included 500 patients (898 eyes) with mean follow-up duration of 15.8 years (10-25 years), and 81% patients had bilateral disease. Patients using oral steroid during acute stage disease had significantly better visual outcome at the final visit [0.42 logMar(6/18) ± 0.723 logMar(6/30)] compared to patients who did not receive oral steroids [(0.5907 logMar(6/24) ± 0.945 logMar(6/48)] (p = 0.004). Patients who received laser therapy had significantly better visual outcome at the final visit [(0.415 logMar(6/18) ± 0.66 logMar(6/30)] compared to those who did not undergo laser treatment [(0.9237 logMar(6/48) ± 1.31 logMar(6/120)] (p < 0.001). Poor presenting visual acuity and late stage of presentation were associated with poor visual outcome. Fifty-two percent of eyes had <5 recurrences over 10 years.
Eales' disease is a bilateral recurrent retinal vasculitis disorder and timely treatment with steroid and/or laser photocoagulation result in better visual outcomes.
分析 Eales 病患者的长期视力结果。
回顾性分析 1985 年至 1995 年间诊断为 Eales 病且随访时间超过 10 年的患者。
我们纳入了 500 名患者（898 只眼），平均随访时间为 15.8 年（10-25 年），81%的患者患有双侧疾病。在急性阶段使用口服类固醇治疗的患者在最终随访时的视力结果明显更好[0.42 logMar(6/18) ± 0.723 logMar(6/30)]，而未接受口服类固醇治疗的患者则较差[0.5907 logMar(6/24) ± 0.945 logMar(6/48)]（p = 0.004）。接受激光治疗的患者在最终随访时的视力结果明显更好[0.415 logMar(6/18) ± 0.66 logMar(6/30)]，而未接受激光治疗的患者则较差[0.9237 logMar(6/48) ± 1.31 logMar(6/120)]（p < 0.001）。较差的初始视力和晚期就诊与较差的视力结果相关。52%的眼睛在 10 年内的复发次数少于 5 次。
Eales 病是一种双侧复发性视网膜血管炎疾病，及时使用类固醇和/或激光光凝治疗可获得更好的视力结果。
