Ryan C A, Willan A R, Wherrett B A
Department of Pediatrics, Hotel Dieu Hospital, Queen's University, Kingston, Ontario, Canada.
Clin Pediatr (Phila). 1988 Sep;27(9):420-4. doi: 10.1177/000992288802700902.
Seventy five percent of 91 parents of asthmatic children (aged 6 months to 15.4 years) with home nebulizers, responded to a questionnaire that sought to document parental experience with this form of therapy. The most common indications for acquiring a nebulizer were inability to use metered dose inhalers and poor response or intolerance to oral medications. When the children were classified into those who used the nebulizer daily (27/69) and those who used it less than daily (42/69), we found that the daily users were more likely to be in the severest category of asthma, by parental assessment, prior to the home nebulization program (p = 0.0035). Retrospective, uncontrolled comparison before and after the acquisition of a home nebulizer showed significant decreases both in hospital admissions (1.7 vs 0.7; p less than 0.001) and total in-patient days (4.1 vs 1.7; p less than 0.0001). Home nebulizers are well tolerated by parents and children alike and may be associated with decreased morbidity.
91名患有哮喘的儿童（年龄在6个月至15.4岁之间）的家长中有家用雾化器，其中75%对一份旨在记录家长使用这种治疗方式经历的问卷做出了回应。购买雾化器最常见的原因是无法使用定量吸入器以及对口服药物反应不佳或不耐受。当将这些孩子分为每天使用雾化器的孩子（27/69）和并非每天使用雾化器的孩子（42/69）时，我们发现，在家用雾化治疗方案实施前，经家长评估，每天使用雾化器的孩子更有可能处于最严重的哮喘类别（p = 0.0035）。对购买家用雾化器前后进行回顾性、非对照比较显示，住院次数（1.7次对0.7次；p<0.001）和住院总天数（4.1天对1.7天；p<0.0001）均显著减少。家长和孩子对家用雾化器的耐受性都很好，而且它可能与发病率降低有关。
