Methyl Transfer from Methanol to Co-cobyrinate: A model for the Coenzyme B Dependent Methyltransferase?
作者信息
Schnyder Alexander, Darbre Tamis, Keese Reinhart
机构信息
Departement für Chemie und Biochemie der Universität, Freiestrasse 3, CH-3012 Bern (Switzerland), Fax: (+41) 31 631 3423.
出版信息
Angew Chem Int Ed Engl. 1998 May 18;37(9):1283-1285. doi: 10.1002/(SICI)1521-3773(19980518)37:9<1283::AID-ANIE1283>3.0.CO;2-N.
Abstract
With Co corrins as supernucleophiles, methylation by methanol is achieved when the leaving group is activated by Zn ions at elevated temperatures (see reaction below). This methylation reaction is the first model for the Co-dependent methyltransferase.
摘要
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