Hospital Interzonal San Martín, La Plata, Argentina.
Facultad de Ciencias Médicas, UNLP, La Plata, Argentina.
J Hum Hypertens. 2018 Jun;32(6):415-422. doi: 10.1038/s41371-018-0057-y. Epub 2018 May 1.
Blood pressure (BP) was assessed by patients themselves in recently published trials. Self-measured office blood pressure (SMOBP) seems particularly interesting for limited health resources regions. The aim of our study was to evaluate the relationship between SMOBP values and those estimated by ambulatory blood pressure monitoring (ABPM). Six hundred seventy-seven patients were evaluated using both, SMOBP and ABPM. The differences between SMOBP and daytime ABPM were evaluated with paired "t" test. The correlations among SMOBP and ABPM were estimated using Pearson's r. The accuracy of SMOBP to identify abnormal ABPM was determined using area under ROC curve (AUC). Sensitivity, specificity, and positive and negative predictive values were calculated for different SMOBP cut-points. Using the average of three readings, systolic SMOBP was higher (3.7 (14.2) mmHg, p < 0.001) and diastolic SMOBP lower (1.5 (8.1) mmHg, p < 0.001) than ABPM. Both BP estimates had a significant correlation, r = 0.67 and r = 0.75 (p < 0.01) for systolic and diastolic BP, respectively. Systolic SMOBP predicted systolic abnormal ABPM; the AUC were 0.80 (0.77-0.84) and 0.78 (0.74-0.81) for daytime and 24 h hypertension, respectively. Diastolic SMOBP predicted diastolic hypertension, AUC 0.86 (0.83-0.88) for both daytime and 24 h hypertension. Neither correlations nor AUCs improved significantly using the average of five readings. SMOBP ≥ 160/90 mmHg was highly specific (>95%) to identify individuals with hypertension in the ABPM; SMOBP < 130/80 mmHg reasonably discarded abnormal ABPM. In conclusion, a high proportion of individuals could be classified adequately using SMOBP, reducing the necessity of healthcare resources and supporting its utility for screening purposes.
血压(BP)在最近发表的试验中由患者自行评估。自我测量诊室血压(SMOBP)似乎特别适用于医疗资源有限的地区。我们的研究目的是评估 SMOBP 值与动态血压监测(ABPM)估计值之间的关系。使用 SMOBP 和 ABPM 评估了 677 名患者。使用配对“t”检验评估 SMOBP 与日间 ABPM 之间的差异。使用 Pearson's r 估计 SMOBP 与 ABPM 之间的相关性。使用 ROC 曲线下面积(AUC)确定 SMOBP 识别异常 ABPM 的准确性。计算不同 SMOBP 切点的 AUC、敏感度、特异度、阳性和阴性预测值。使用三次读数的平均值,收缩压 SMOBP 较高(3.7(14.2)mmHg,p<0.001),舒张压 SMOBP 较低(1.5(8.1)mmHg,p<0.001)。两种血压估计均具有显著相关性,收缩压和舒张压的 r 值分别为 0.67 和 0.75(p<0.01)。收缩压 SMOBP 预测收缩压异常 ABPM;日间和 24 小时高血压的 AUC 分别为 0.80(0.77-0.84)和 0.78(0.74-0.81)。舒张压 SMOBP 预测舒张压高血压,日间和 24 小时高血压的 AUC 分别为 0.86(0.83-0.88)。使用五次读数的平均值后,相关性或 AUC 均未显著改善。SMOBP≥160/90mmHg 高度特异(>95%),可识别 ABPM 中的高血压患者;SMOBP<130/80mmHg 可合理排除异常 ABPM。总之,使用 SMOBP 可对相当一部分个体进行适当分类,减少医疗资源的需求,并支持其用于筛查目的。