Deng Zhen, Wang Huihao, Niu Wenxin, Lan Tianying, Wang Kuan, Zhan Hongsheng
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2016 Aug;33(4):652-8.
This study aims to develop and validate a three-dimensional finite element model of inferior cervical spinal segments C4-7of a healthy volunteer,and to provide a computational platform for investigating the biomechanical mechanism of treating cervical vertebra disease with Traditional Chinese Traumotology Manipulation(TCTM).A series of computed tomography(CT)images of C4-7segments were processed to establish the finite element model using softwares Mimics 17.0,Geromagic12.0,and Abaqus 6.13.A reference point(RP)was created on the endplate of C4 and coupled with all nodes of C4.All loads(±0.5,±1,±1.5and±2Nm)were added to the RP for the six simulations(flexion,extension,lateral bending and axial rotation).Then,the range of motion of each segment was calculated and compared with experimental measurements of in vitro studies.On the other hand,1Nm moment was loaded on the model to observe the main stress regions of the model in different status.We successfully established a detail model of inferior cervical spinal segments C4-7of a healthy volunteer with 591 459 elements and 121 446 nodes which contains the structure of the vertebra,intervertebral discs,ligaments and facet joints.The model showed an accordance result after the comparison with the in vitro studies in the six simulations.Moreover,the main stress region occurred on the model could reflect the main stress distribution of normal human cervical spine.The model is accurate and realistic which is consistent with the biomechanical properties of the cervical spine.The model can be used to explore the biomechanical mechanism of treating cervical vertebra disease with TCTM.
本研究旨在建立并验证一名健康志愿者下颈椎C4 - 7节段的三维有限元模型,为研究中医骨伤手法治疗颈椎病的生物力学机制提供一个计算平台。利用Mimics 17.0、Geromagic12.0和Abaqus 6.13软件对C4 - 7节段的一系列计算机断层扫描(CT)图像进行处理,以建立有限元模型。在C4终板上创建一个参考点(RP),并将其与C4的所有节点耦合。在六个模拟(前屈、后伸、侧屈和轴向旋转)中,将所有载荷(±0.5、±1、±1.5和±2 Nm)施加到RP上。然后,计算每个节段的运动范围,并与体外研究的实验测量结果进行比较。另一方面,在模型上施加1 Nm的力矩,以观察模型在不同状态下的主应力区域。我们成功建立了一名健康志愿者下颈椎C4 - 7节段的详细模型,该模型有591459个单元和121446个节点,包含椎体、椎间盘、韧带和小关节的结构。在六个模拟中,该模型与体外研究比较后显示出一致的结果。此外,模型上出现的主应力区域能够反映正常人颈椎的主应力分布。该模型准确且逼真,与颈椎的生物力学特性一致。该模型可用于探索中医骨伤手法治疗颈椎病的生物力学机制。