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肯尼亚基安布县孕妇铁和叶酸补充(IFAS)依从性及其相关因素的横断面研究结果。

Compliance with Iron and folic acid supplementation (IFAS) and associated factors among pregnant women: results from a cross-sectional study in Kiambu County, Kenya.

机构信息

School of Nursing Sciences, College of Health Sciences, University of Nairobi, Nairobi, Kenya.

出版信息

BMC Public Health. 2018 May 2;18(1):580. doi: 10.1186/s12889-018-5437-2.

Abstract

BACKGROUND

Macro and micronutrients including iron and folic acid deficiencies are prevalent in Kenya, particularly during pregnancy resulting in anaemia. Despite efforts to control anaemia in pregnancy by adopting Iron and Folic Acid Supplementation (IFAS), this public health problem has persisted contributing to significant morbidity and mortality. The problem notwithstanding, there is poor IFAS compliance, whose reasons remain poorly understood, calling for their investigations. We sought to determine compliance status with IFAS and associated factors among pregnant women.

METHODS

This was a cross-sectional study involving 364 pregnant women aged 15-49 years. Using two stage cluster sampling, one Sub-County and five public health facilities in Kiambu County were selected. All pregnant women attending antenatal clinics who met inclusion criteria and consented to participate in the study were recruited. Compliance with IFAS was defined as taking supplements at least 5 out of 7 days per week. A structured interviewer-administered questionnaire consisting of sociodemographic data, IFAS maternal knowledge and compliance practices was pretested and administered. Descriptive and inferential statistics were computed using STATA.

RESULTS

Of the 364 respondents interviewed, 32.7% were IFAS compliant and 40.9% scored high on its knowledge. Of those with high IFAS knowledge, 48.3% were compliant compared to those with low knowledge (21.4%, n = 46, PR = 2.25;95%CI = 1.59-3.17, p < 0.001). Women who were multigravid (30.4%) were less likely to comply compared to primigravid (37.2%, n = 45, PR = 0.68;95%CI = 0.47-0.99, p = 0.004). Multivariate analysis revealed that respondents counselled on management of IFAS side effects (100%, n = 4) were more compliant (76.2%, n = 112, aPR = 1.31;95%CI = 1.19-1.44, p < 0.001).

CONCLUSION

Few pregnant women were compliant with IFAS regimen, associated with: knowledgeability on IFAS, primi-gravidity, and IFAS counselling especially on management of its side effects. These underscore the need for approaches to scale up health awareness on the benefits of IFAS, mitigation measures for the side effects, as well as targeted counselling.

摘要

背景

肯尼亚普遍存在宏量和微量营养素(包括铁和叶酸)缺乏症,尤其是在怀孕期间,这会导致贫血。尽管通过采用铁和叶酸补充剂(IFAS)来控制孕期贫血,但这一公共卫生问题仍持续存在,导致了显著的发病率和死亡率。尽管存在这一问题,但 IFAS 的依从性仍然很差,其原因尚不清楚,需要对其进行调查。我们旨在确定孕妇对 IFAS 的依从情况及其相关因素。

方法

这是一项横断面研究,涉及 364 名 15-49 岁的孕妇。采用两阶段整群抽样方法,在基安布县选择了一个次级县和五个公共卫生设施。所有符合纳入标准并同意参加研究的在产前诊所就诊的孕妇均被招募。IFAS 依从性定义为每周至少服用 7 天中的 5 天。使用经过预测试的结构化访谈者管理问卷,其中包括社会人口统计学数据、IFAS 产妇知识和依从性实践。使用 STATA 计算描述性和推断性统计数据。

结果

在接受采访的 364 名受访者中,32.7%的人符合 IFAS 规定,40.9%的人对其知识评分较高。在那些具有较高 IFAS 知识的人中,48.3%的人是依从的,而那些知识较低的人(21.4%,n=46,PR=2.25;95%CI=1.59-3.17,p<0.001)。与初产妇(37.2%,n=45,PR=0.68;95%CI=0.47-0.99,p=0.004)相比,多产妇(30.4%)不太可能遵守。多变量分析显示,接受 IFAS 副作用管理咨询的受访者(100%,n=4)更依从(76.2%,n=112,aPR=1.31;95%CI=1.19-1.44,p<0.001)。

结论

很少有孕妇符合 IFAS 方案,这与 IFAS 知识、初产妇、IFAS 咨询有关,特别是关于其副作用的管理。这突显出需要采取措施提高对 IFAS 益处的健康意识,减轻副作用的缓解措施,以及有针对性的咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f72/5930505/713d6938aacc/12889_2018_5437_Fig1_HTML.jpg

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