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运动神经传导研究在特发性跗管综合征诊断中的价值:一项来自印度的单中心前瞻性观察研究。

Value of Motor Nerve Conduction Studies in the Diagnosis of Idiopathic Tarsal Tunnel Syndrome: A Single-center Prospective Observational Study from India.

作者信息

Sodani Ajoy, Dube Mukesh, Jain Rahul

机构信息

Department of Neurology, Sri Aurobindo Medical College and Postgraduate Institute, Indore, Madhya Pradesh, India.

出版信息

Ann Indian Acad Neurol. 2018 Jan-Mar;21(1):35-41. doi: 10.4103/aian.AIAN_320_17.

Abstract

BACKGROUND

Nerve conduction studies are considered to be the gold standard for diagnosing secondary tarsal tunnel syndrome (s TTS), but their utility in the diagnosis of idiopathic tarsal tunnel syndrome (i TTS) is largely unknown.

OBJECTIVE

We sought to investigate the value of motor nerve conductions studies (MNCS) in the diagnosis of clinically suspected TTS.

MATERIALS AND METHODS

Twenty-six (52 limbs) adult patients of clinically suspected TTS were subjected to motor nerve conductions of posterior tibial nerve, and its branches and motor conduction parameters were compared with those of 45 healthy controls.

RESULTS

Symptoms were bilateral in 70% ( = 0.02), with heel pain in 95% of symptomatic limbs. MNCS was abnormal in 32 (80%) of symptomatic limbs and 8 (66.6%) of asymptomatic limbs ( = 0.004). Out of electrophysiologically abnormal nerves ( = 67), the pathological process could be identified in all the nerves with abnormal MNCS ( = 0.02). Probable demyelination was seen in 58.2% of the electrophysiologically abnormal nerves.

DISCUSSION

The present study shows that TTS are gender and Body Mass Index neutral with bilateral symptoms being common. Tinel's sign was inconsistent. Heel pain did not correlate with abnormal inferior calcaneal nerve conductions. Motor nerve conduction study was abnormal in a significant number of symptomatic limbs. "Probable demyelination" was more frequent in symptomatic limbs.

CONCLUSION

MNCS is significantly abnormal in symptomatic limbs of subjects with TTS. Demyelination is slightly more common than axonopathy in TTS. With a sensitivity of 80% and specificity of 33.3%, MNCS seems to be useful as a screening tool in clinically suspected TTS. This study is Level II: Lesser quality randomized controlled trial or prospective comparative study.

摘要

背景

神经传导研究被认为是诊断继发性跗管综合征(sTTS)的金标准,但其在特发性跗管综合征(iTTS)诊断中的作用很大程度上尚不清楚。

目的

我们试图研究运动神经传导研究(MNCS)在临床疑似跗管综合征诊断中的价值。

材料与方法

对26例(52条肢体)临床疑似跗管综合征的成年患者进行胫后神经运动神经传导检查,并将其分支及运动传导参数与45例健康对照者进行比较。

结果

70%的患者症状为双侧性(P = 0.02),95%有症状的肢体出现足跟疼痛。有症状肢体中32例(80%)MNCS异常,无症状肢体中8例(66.6%)异常(P = 0.004)。在电生理异常的神经中(n = 67),所有MNCS异常的神经均能确定病理过程(P = 0.02)。在58.2%的电生理异常神经中可见可能的脱髓鞘改变。

讨论

本研究表明,跗管综合征与性别和体重指数无关,双侧症状常见。Tinel征不一致。足跟疼痛与跟骨下神经传导异常无关。大量有症状的肢体运动神经传导研究异常。“可能的脱髓鞘”在有症状的肢体中更常见。

结论

跗管综合征患者有症状肢体的MNCS明显异常。在跗管综合征中,脱髓鞘比轴索性病变稍常见。MNCS敏感性为80%,特异性为33.3%,似乎可作为临床疑似跗管综合征的筛查工具。本研究为II级:质量较低的随机对照试验或前瞻性比较研究。

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本文引用的文献

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Proposed Sonographic Criteria for the Diagnosis of Idiopathic Tarsal Tunnel Syndrome.特发性跗管综合征诊断的超声检查标准建议
Arch Phys Med Rehabil. 2016 Jul;97(7):1093-9. doi: 10.1016/j.apmr.2015.11.012. Epub 2015 Dec 17.
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Neuroanatomical basis for the tarsal tunnel syndrome.跗管综合征的神经解剖学基础。
Foot Ankle Int. 2012 Jun;33(6):513-8. doi: 10.3113/FAI.2012.0513.
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Posterior tarsal tunnel syndrome: diagnosis and treatment.跗骨后隧道综合征:诊断与治疗。
Dtsch Arztebl Int. 2008 Nov;105(45):776-81. doi: 10.3238/arztebl.2008.0776. Epub 2008 Nov 7.

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