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跗管手术中术前临床症状和电诊断数据的预测性结果建模

Predictive Outcome Modeling of Preoperative Clinical Symptoms and Electrodiagnostic Data in Tarsal Tunnel Surgery.

作者信息

Seidel Geoffrey K, Jamal Salma Al, Weidert Eric, Carington Frederick, Andary Michael T, Millis Scott R, Loder Brian G

机构信息

Department of Physical Medicine and Rehabilitation, Wayne State University School of Medicine, Michigan State University College of Osteopathic Medicine, Henry Ford Macomb Hospital, Clinton Township, Michigan, United States.

Department of Obstetrics and Gynecology, Advocate Aurora Health, Aurora Healthcare, Milwaukee, Wisconsin, United States.

出版信息

J Brachial Plex Peripher Nerve Inj. 2021 Jul 27;16(1):e37-e45. doi: 10.1055/s-0041-1731747. eCollection 2021 Jan.

Abstract

The relationship between tarsal tunnel syndrome (TTS), electrodiagnostic (Edx) findings, and surgical outcome is unknown. Analysis of TTS surgical release outcome patient satisfaction and comparison to Edx nerve conduction studies (NCSs) is important to improve outcome prediction when deciding who would benefit from TTS release.  Retrospective study of 90 patients over 7 years that had tarsal tunnel (TT) release surgery with outcome rating and preoperative tibial NCS. Overall, 64 patients met study inclusion criteria with enough NCS data to be classified into one of the following three groups: (1) probable TTS, (2) peripheral polyneuropathy, or (3) normal. Most patients had preoperative clinical provocative testing including diagnostic tibial nerve injection, tibial Phalen's sign, and/or Tinel's sign and complaints of plantar tibial neuropathic symptoms. Outcome measure was percentage of patient improvement report at surgical follow-up visit.  Patient-reported improvement was 92% in the probable TTS group (  = 41) and 77% of the non-TTS group (  = 23). Multivariate modeling revealed that three out of eight variables predicted improvement from surgical release, NCS consistent with TTS (  = 0.04), neuropathic symptoms (  = 0.045), and absent Phalen's test (  = 0.001). The was 0.21 which is a robust result for this outcome measurement process.  The best predictors of improvement in patients with TTS release were found in patients that had preoperative Edx evidence of tibial neuropathy in the TT and tibial nerve plantar symptoms. Determining what factors predict surgical outcome will require prospective evaluation and evaluation of patients with other nonsurgical modalities.

摘要

跗管综合征(TTS)、电诊断(Edx)结果与手术效果之间的关系尚不清楚。分析TTS手术松解的效果、患者满意度,并与Edx神经传导研究(NCS)进行比较,对于在决定谁将从TTS松解术中获益时改善预后预测非常重要。

对90例患者进行了为期7年的回顾性研究,这些患者接受了跗管(TT)松解手术,并进行了预后评级和术前胫神经NCS检查。总体而言,64例患者符合研究纳入标准,有足够的NCS数据可分为以下三组之一:(1)可能的TTS,(2)周围性多发性神经病,或(3)正常。大多数患者术前进行了临床激发试验,包括诊断性胫神经注射、胫神经Phalen征和/或Tinel征,以及足底胫神经病变症状的主诉。预后指标是手术随访时患者报告的改善百分比。

在可能的TTS组(n = 41)中,患者报告的改善率为92%,在非TTS组(n = 23)中为77%。多变量建模显示,八个变量中的三个预测了手术松解后的改善情况,NCS与TTS一致(P = 0.04)、神经病变症状(P = 0.045)和Phalen试验阴性(P = 0.001)。C统计量为0.21,对于这个预后测量过程来说是一个可靠的结果。

TTS松解患者改善的最佳预测因素是术前Edx有TT胫神经病变证据和胫神经足底症状患者。确定哪些因素可预测手术效果需要进行前瞻性评估以及对采用其他非手术方式治疗的患者进行评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e2e/8315987/10444924e43f/10-1055-s-0041-1731747-i2100001-1.jpg

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