Richard Seidu A, Lan Zhi Gang, Yang Xiao, Huang Siqing
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China.
Pediatr Rep. 2018 Mar 22;10(1):7339. doi: 10.4081/pr.2018.7339.
Atlantoaxial dislocation is a disorder that is characterized with loss of stability of the atlas and axis (C1-C2) with consequential loss of usual articulation. Although this condition is very common, no one has reported a case as young as our patients. We present a 7-month infant with bilateral paralysis of the lower limbs for four (4) months with no history of trauma. Computer tomographic (CT-scan) imaging revealed alantoaxial dislocation with severe cervical spinal cord compression. The odontoid process is displaced outwardly with no bone destruction. Doppler echocardiogram done revealed patent foramen ovale. Thorough physical examination as well as radiological evaluation revealed no feather malformations. Electrophysio - logical studies reveal normal compound muscle action potentials (CMAP) and sensory nerve action potentials (SNAPs) in all the limbs. Electromyography (EMG) also revealed normal nerves in the limbs and the trunk. We attained a stable fusion and anatomical reduction using a posterior titanium wire and an iliac bone graft harvested from his mother. This is the youngest patient reported in literature. Infantile alantoaxial dislocation should be managed at early stage to prevent long-term neurologic disorders.
寰枢椎脱位是一种以寰椎和枢椎(C1-C2)稳定性丧失以及随之而来的正常关节活动丧失为特征的疾病。尽管这种情况很常见,但尚无人像我们的患者这般年幼的病例报道。我们报告一例7个月大的婴儿,双下肢瘫痪4个月,无外伤史。计算机断层扫描(CT扫描)成像显示寰枢椎脱位并伴有严重的颈脊髓压迫。齿状突向外移位,无骨质破坏。经胸超声心动图检查显示卵圆孔未闭。全面的体格检查以及影像学评估未发现脊柱裂畸形。电生理研究显示所有肢体的复合肌肉动作电位(CMAP)和感觉神经动作电位(SNAPs)均正常。肌电图(EMG)也显示四肢和躯干的神经正常。我们使用从其母亲身上采集的自体髂骨移植并结合后路钛丝固定,实现了稳定融合和解剖复位。这是文献报道中最年幼的患者。小儿寰枢椎脱位应尽早治疗,以预防长期神经功能障碍。