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多排螺旋计算机断层扫描在评估具有手术相关性的急性阑尾炎临床疑似病例中的诊断效能

Diagnostic Efficiency of Multidetector Computed Tomography in the Evaluation of Clinically Equivocal Cases of Acute Appendicitis with Surgical Correlation.

作者信息

Iqbal Jawaid, Sayani Raza, Tahir Misbah, Mustahsan Syed M

机构信息

Radiology, Liaquat National Hospital and Medical College.

Department of Radiology, The Aga Khan University Hospital, Karachi.

出版信息

Cureus. 2018 Mar 1;10(3):e2249. doi: 10.7759/cureus.2249.

Abstract

Acute appendicitis is one of the most frequent causes of lower abdominal pain and requires immediate surgical intervention. The diagnosis often poses a lot of challenge even to experienced surgeon. Those patients with equivocal symptoms may require different imaging modalities like radiography, contrast examination and ultrasound with limited utility. Multidetector computed tomography (MDCT) used in suspected acute appendicitis has, however, resulted in improved diagnostic accuracy and also reduction of negative surgeries. Objective We intend to determine the diagnostic efficiency of MDCT in clinically equivocal cases of acute appendicitis correlating it with surgical/histopathological findings. Materials and methods A group of 116 patients was included in this study. Spiral MDCT was performed in all these cases after administration of oral and intravenous contrast. All these patients underwent surgery and the CT findings were correlated with histopathology. Out of these 116 patients, 60 patients were male and 56 female. The age range was from three to seventy years and mean age was 28+1 years. Results The results proved that MDCT had a sensitivity of 97.5%, specificity of 97.0%, and accuracy of 97.4% for the diagnosis of appendicitis with one false positive and two false negative cases. The study showed 100% accuracy in diagnosing acute appendicitis in children. In 33 patients, an alternate cause was identified with CT. The alternate diagnosis made on CT findings was consistent with the final diagnosis in 27 (81.8%) of 33 patients in whom there was no evidence of acute appendicitis. The clinical diagnosis disagreed with the CT diagnosis in six patients (18.18%). Conclusion Our study verifies that MDCT plays an important role in evaluation and consequent management of equivocal cases of acute appendicitis. MDCT is also able to diagnose appendicitis or detect alternative diagnosis in pediatric population.

摘要

急性阑尾炎是下腹部疼痛最常见的病因之一,需要立即进行手术干预。即使对于经验丰富的外科医生来说,诊断也常常具有很大的挑战性。那些症状不明确的患者可能需要采用不同的成像方式,如放射照相、造影检查和超声检查,但这些方法的效用有限。然而,在疑似急性阑尾炎中使用多排螺旋计算机断层扫描(MDCT)提高了诊断准确性,也减少了阴性手术的发生。目的我们旨在确定MDCT在临床症状不明确的急性阑尾炎病例中的诊断效率,并将其与手术/组织病理学结果进行关联。材料与方法本研究纳入了一组116例患者。所有这些病例在口服和静脉注射造影剂后均进行了螺旋MDCT检查。所有这些患者均接受了手术,CT检查结果与组织病理学结果进行了关联。在这116例患者中,男性60例,女性56例。年龄范围为3至70岁,平均年龄为28±1岁。结果结果证明,MDCT诊断阑尾炎的敏感性为97.5%,特异性为97.0%,准确性为97.4%,有1例假阳性和2例假阴性病例。该研究显示在诊断儿童急性阑尾炎方面准确率为100%。在33例患者中,CT发现了其他病因。根据CT检查结果做出的其他诊断与最终诊断一致,在33例无急性阑尾炎证据的患者中有27例(81.8%)。6例患者(18.18%)的临床诊断与CT诊断不一致。结论我们的研究证实,MDCT在评估以及后续处理临床症状不明确的急性阑尾炎病例中发挥着重要作用。MDCT还能够诊断阑尾炎或在儿童群体中检测出其他诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf2/5929941/f6040d9b22f3/cureus-0010-00000002249-i01.jpg

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