Bahl A, Singh R, Wadhwa J, Gupta S, Ahmed M, Uppal P N, Parikh Purvish M, Aggarwal S
Deparment of Medical Oncology, Max Hospital, New Delhi, India.
Department of Medical Oncology, Artemis Hospital, Gurugram, India.
South Asian J Cancer. 2018 Apr-Jun;7(2):102-105. doi: 10.4103/sajc.sajc_111_18.
Over-expression of HER2 is generally considered to be a negative prognostic feature because it accompanies an increase in breast cancer mortality. However, the development of agents that specifically target HER2 has improved the management of patients with these tumours. This expert group used data from published literature, practical experience and opinion of a large group of academic oncologists to arrive at these practical consensus recommendations with regards to the use of these agents and the management of HER2 neu early breast cancer for the benefit of community oncologists.
HER2的过度表达通常被认为是一种不良预后特征,因为它伴随着乳腺癌死亡率的增加。然而,特异性靶向HER2的药物的开发改善了这些肿瘤患者的治疗。该专家组利用已发表文献的数据、实践经验以及一大批学术肿瘤学家的意见,就这些药物的使用以及HER2阳性早期乳腺癌的治疗达成了这些实用的共识建议,以造福社区肿瘤学家。