Hazan Ori, Sternik Leonid, Waiss Dar, Eldar Michael, Hoffer Oshrit, Goitein Orly, Kuperstein Rafael, Konen Eli, Ovadia-Blechman Zehava
a The Sackler Faculty of Medicine , Tel Aviv University , Ramat Aviv , Israel.
b School of Medical Engineering , Afeka -Tel Aviv Academic College of Engineering , Tel-Aviv , Israel.
Comput Methods Biomech Biomed Engin. 2018 Mar;21(4):370-378. doi: 10.1080/10255842.2018.1466116.
Invagination is an innovative technique for closing the left atrial appendage (LAA) to reduce the risk of thrombi formation. The influence of LAA invagination on the flow fields in the atria was investigated based on a computational fluid dynamics. The simulation results demonstrated that the novel invagination process can eliminate low velocities (blood stasis) and low shear rate and thus decrease the risk of thrombus formation during atrial fibrillation. This innovative technique may enhance the clinical treatment of patients with atrial fibrillation by improving the atrial flow field while lowering the risk of creating emboli.
内陷术是一种用于闭合左心耳（LAA）以降低血栓形成风险的创新技术。基于计算流体动力学研究了LAA内陷术对心房内流场的影响。模拟结果表明，这种新型内陷术可消除低速（血流淤滞）和低剪切率，从而降低房颤期间血栓形成的风险。这项创新技术可能通过改善心房流场并降低产生栓子的风险来加强房颤患者的临床治疗。
