Cardona Ricardo, Sánchez Andrés, Larenas-Linnemann Désirée, Járes Edgardo, Sánchez Jorge
Universidad de Antioquia, Servicio Alergología Clínica. Grupo de Alergología Clínica y Experimental, Medellín, Antioquia, Colombia.
Rev Alerg Mex. 2018 Jan-Mar;65(1):25-40. doi: 10.29262/ram.v65i1.287.
The Latin American Society of Allergy, Asthma, and Immunology (SLAAI) presents a document about the use of immunotherapy (IT) in Latin America, where administration patterns, indications and contraindications, effects on health, adverse events and socioeconomic impact are reviewed.
To review publications analyzing the use of IT in Latin America.
A literature review was carried out in order to identify works addressing IT in Latin America. This review was focused on practical scientific information available on IT in the region, and a parallel comparison was made with practices observed in the United States and European countries.
Of the 21 Latin American countries included, only 9 had original articles meeting the selection criteria; a total of 82 articles were selected, most of them from Brazil and Mexico. Most widely used allergenic extracts in Latin America tropical and subtropical regions were those of mites and pollen.
Although it is true that there are huge challenges for the future of IT in Latin America, studies on subcutaneous IT and sublingual IT are increasing, but most of them are retrospective and some have design bias, and more prospective studies are therefore required, using internationally validated scales for clinical evaluation.
拉丁美洲过敏、哮喘与免疫学协会（SLAAI）发布了一份关于拉丁美洲免疫疗法（IT）使用情况的文件，其中回顾了给药模式、适应证与禁忌证、对健康的影响、不良事件及社会经济影响。
回顾分析拉丁美洲免疫疗法使用情况的出版物。
进行文献综述以确定涉及拉丁美洲免疫疗法的研究。该综述聚焦于该地区免疫疗法的实用科学信息，并与美国和欧洲国家观察到的实践进行平行比较。
在所纳入的21个拉丁美洲国家中，只有9个国家有符合入选标准的原创文章；共筛选出82篇文章，其中大部分来自巴西和墨西哥。拉丁美洲热带和亚热带地区最常用的变应原提取物是螨和花粉的提取物。
尽管拉丁美洲免疫疗法的未来确实面临巨大挑战，但皮下免疫疗法和舌下免疫疗法的研究正在增加，但其中大多数是回顾性的，有些存在设计偏差，因此需要更多前瞻性研究，并使用国际认可的临床评估量表。
