Collado-Chagoya Rodrigo, Hernández-Romero Javier, Eliosa-Alvarado Gumaro Alejandro, García-González Ana Carmen, Campos-Gutiérrez Rosa Isela, Velasco-Medina Andrea, Velázquez-Sámano Guillermo
Secretaría de Salud, Hospital General de México, Servicio de Inmunología Clínica y Alergia, Ciudad de México, México.
Rev Alerg Mex. 2018 Jan-Mar;65(1):103-107. doi: 10.29262/ram.v65i1.282.
Psyllium is a derivative of Plantago ovata ground seed and husk that is used as bulk-forming laxatives owing to its hydrocolloid properties.
43-year-old female nurse with previous diagnosis of drug allergy and allergic rhinitis who, after the preparation and administration of a laxative, developed rhinoconjunctivitis symptoms, urticarial syndrome, angioedema and bronchospasm, which led to conclude that she had an anaphylactic reaction. She was treated with adrenaline, corticosteroids and antihistamines. After symptom resolution, with in vivo tests by means of the skin prick technique and by in vitro assay (specific IgE), hypersensitivity to plantago psyllium was determined.
Most cases of anaphylaxis have been reported with psyllium ingestion, since, through that route, antigenic burden is higher. It should be noted that, even when exposure in the described patient was only by inhalation, manifestations were life-threatening.
车前草籽是卵叶车前草磨碎的种子和外壳的衍生物,因其水胶体特性而用作容积性泻药。
一名43岁的女护士,既往诊断有药物过敏和过敏性鼻炎,在制备和服用一种泻药后,出现鼻结膜炎症状、荨麻疹综合征、血管性水肿和支气管痉挛,从而推断她发生了过敏反应。她接受了肾上腺素、皮质类固醇和抗组胺药治疗。症状缓解后,通过皮肤点刺技术进行体内试验和体外检测(特异性IgE),确定对卵叶车前草过敏。
大多数过敏反应病例报告是因摄入车前草籽引起的,因为通过该途径,抗原负荷更高。应当指出的是,即使在所描述的患者中仅通过吸入接触,其表现也危及生命。