Sussman G L, Dorian W
University of Toronto, Division of Immunology, Wellesley Hospital, Canada.
Allergy Proc. 1990 Sep-Oct;11(5):241-2. doi: 10.2500/108854190778879828.
Allergic reactions from handling psyllium have been reported since 1970. Health professionals and workers in laxative-manufacturing plants are at greatest risk. Sensitized people are at risk of life-threatening anaphylactic reactions. Two illustrative cases are presented. The first is A 39-year-old female dialysis nurse with a 3-year history of nasal and eye symptoms from exposure to psyllium. She obtained an over-the-counter psyllium bulk laxative, took it for constipation and developed flushing, tachycardia, urticaria, angioedema, laryngeal edema, and lightheadedness. An epicutaneous skin test and radioallergosorbent test for psyllium were both strongly positive. The second is a 42-year-old female nurse with a history of asthma who had allergic nasal and eye symptoms while dispensing psyllium. She received a prescription for crystallized psyllium, took it by mouth, and developed immediate flushing, tachycardia, urticaria, and angioedema. With subsequent ingestion of psyllium she had, in addition, severe wheezing, lightheadedness, and loss of consciousness. A psyllium epicutaneous skin test was strongly positive. These patient reports illustrate the risk of severe allergic reactions in sensitized people. Ingestion by sensitized people, such as from a routine postoperative and postpartum order, is potentially dangerous.
自1970年以来，已有关于接触车前草引起过敏反应的报道。卫生专业人员和泻药生产厂的工人面临的风险最大。过敏者有发生危及生命的过敏反应的风险。现介绍两个典型案例。第一个案例是一名39岁的女性透析护士，因接触车前草有3年的鼻和眼症状病史。她购买了一种非处方的车前草大容量泻药，用于治疗便秘，随后出现脸红、心动过速、荨麻疹、血管性水肿、喉头水肿和头晕。车前草的皮肤点刺试验和放射变应原吸附试验均呈强阳性。第二个案例是一名42岁有哮喘病史的女性护士，在调配车前草时出现过敏性鼻和眼症状。她收到了一份结晶车前草的处方，口服后立即出现脸红、心动过速、荨麻疹和血管性水肿。随后再次摄入车前草时，她还出现了严重的喘息、头晕和意识丧失。车前草皮肤点刺试验呈强阳性。这些患者报告说明了过敏者发生严重过敏反应的风险。过敏者摄入（如因常规术后和产后医嘱）可能具有危险性。
