Ungerleider R M, Bengur A R, Kessenich A L, Liekweg R J, Hart E M, Rice B A, Miller C E, Lockwood N W, Knauss S A, Jaggers J, Sanders S P, Greeley W J
Department of Nursing Services, Duke University Medical Center, Durham, NC 27712, USA.
Ann Thorac Surg. 1997 Jul;64(1):44-8; discussion 49. doi: 10.1016/s0003-4975(97)00503-1.
For many congenital heart defects, hospital mortality is no longer a sensitive parameter by which to measure outcome. Although hospital survival rates are now excellent for a wide variety of lesions, many patients require expensive and extensive hospital-based services during the perioperative period to enable their convalescence. These services can substantially increase the cost of care delivery. In today's managed care environment, it would be useful if risk factors for higher cost could be identified preoperatively so that appropriate resources could be made available for the care of these patients. The focus of this retrospective investigation is to determine if risk factors for high cost for repair of congenital heart defects can be identified.
We assessed financial risk by tracking actual hospital costs (not charges) for 144 patients undergoing repair of atrial septal defect (58 patients), ventricular septal defect (48 patients), atrioventricular canals (14 patients), or tetralogy of Fallot (24 patients) at Duke University Medical Center between July 1, 1992, and September 15, 1995. Furthermore, we were able to identify where the costs occurred within the hospital. Financial risk was defined as a large (> 60% of mean costs) standard deviation, which indicated unpredictability and variability in the treatment for a group of patients.
Cost for atrial septal defect repair was predictably consistent (low standard deviation) and was related to hospital length of stay. There were factors, however, for ventricular septal defect, atrioventricular canal, and tetralogy of Fallot repair that are identifiable preoperatively that predict low- and high-risk groups using cost as an outcome parameter. Patients undergoing ventricular septal defect repair who were younger than 6 months of age at the time of repair, who required preoperative hospital stays of longer than 7 days before surgical repair, or who had Down's syndrome had a less predictable cost picture than patients undergoing ventricular septal defect repair who were older than 2 years, who had short (< 4 days) preoperative hospitalization, or who did not have Down's syndrome ($48,252 +/- $42,539 versus $15,819 +/- $7,219; p = 0.008). Patients with atrioventricular canals who had long preoperative hospitalization (> 7 days), usually due to pneumonia (respiratory syncytial virus) with preoperative mechanical ventilation had significantly higher cost than patients with atrioventricular canals who underwent elective repair with short preoperative hospitalization ($83,324 +/- $60,138 versus $26,904 +/- $5,384; p = 0.05). Patients with tetralogy of Fallot had higher costs if they had multiple congenital anomalies, previous palliation (combining costs of both surgical procedures and hospital stays), or severe "tet" spells at the time of presentation for operation compared with patients without these risk factors ($114,202 +/- $88,524 versus $22,241 +/- $7,071; p = 0.0005). One patient (with tetralogy of Fallot) with multiple congenital anomalies died 42 days after tetralogy of Fallot repair of sepsis after a gastrointestinal operation. Otherwise, hospital mortality was 0% for all groups.
Low mortality and good long-term outcome for surgical correction of congenital heart defects is now commonplace, but can be expensive as some patients with complex problems receive the care necessary to survive. This study demonstrates that it is possible to identify factors preoperatively that predict financial risk. This knowledge may facilitate implementation of risk adjustments for managed care contracting and for strategic resource allocation.
对于许多先天性心脏缺陷而言,医院死亡率已不再是衡量治疗结果的敏感参数。尽管目前各类心脏病变的医院存活率都很高,但许多患者在围手术期需要昂贵且广泛的医院服务来促进康复。这些服务会大幅增加医疗护理的成本。在当今的管理式医疗环境中,如果能在术前识别出导致高成本的风险因素,以便为这些患者的护理提供适当资源,将是很有帮助的。这项回顾性研究的重点是确定是否能识别出先天性心脏缺陷修复成本高的风险因素。
我们通过追踪1992年7月1日至1995年9月15日在杜克大学医学中心接受房间隔缺损修复(58例患者)、室间隔缺损修复(48例患者)、房室管畸形修复(14例患者)或法洛四联症修复(24例患者)的144例患者的实际医院成本(而非收费)来评估财务风险。此外,我们还能确定成本在医院内的发生位置。财务风险被定义为标准差较大(>平均成本的60%),这表明一组患者治疗的不可预测性和变异性。
房间隔缺损修复的成本可预测地保持一致(标准差低),且与住院时间相关。然而,对于室间隔缺损、房室管畸形和法洛四联症修复,术前可识别出一些因素,以成本作为结果参数来预测低风险和高风险组。在室间隔缺损修复时年龄小于6个月、手术修复前需要住院超过7天或患有唐氏综合征的患者,其成本情况比年龄大于2岁、术前住院时间短(<4天)或没有唐氏综合征的室间隔缺损修复患者更不可预测(48,252美元±42,539美元对15,819美元±7,219美元;p = 0.008)。术前住院时间长(>7天)的房室管畸形患者,通常因肺炎(呼吸道合胞病毒)且术前接受机械通气,其成本显著高于术前住院时间短而接受择期修复的房室管畸形患者(83,324美元±60,138美元对26,904美元±5,384美元;p = 0.05)。与没有这些风险因素的患者相比,患有法洛四联症且有多发性先天性异常、既往姑息治疗(包括手术和住院费用)或手术时出现严重“四联症”发作的患者成本更高(114,202美元±88,524美元对22,241美元±7,071美元;p = 0.0005)。一名患有法洛四联症且有多发性先天性异常的患者在法洛四联症修复术后42天因胃肠道手术后败血症死亡。否则,所有组的医院死亡率均为0%。
先天性心脏缺陷手术矫正的低死亡率和良好的长期预后如今很常见,但由于一些有复杂问题的患者需要接受必要的生存护理,可能会很昂贵。这项研究表明,术前有可能识别出预测财务风险的因素。这些知识可能有助于实施管理式医疗合同的风险调整和战略资源分配。