Ali Ibrahim K, Parate Amit R, Kasat Vikrant O, Dora Amaresh
Oral Medicine and Radiology, Nair Hospital Dental College.
Oral Medicine and Radiology, Govt. Dental College, Aurangabad.
Cureus. 2018 Mar 3;10(3):e2265. doi: 10.7759/cureus.2265.
Multiple myeloma (MM) is a malignant neoplasm of plasma cell origin. It usually has a multicentric origin within the bone. It contributes to about 1% of all malignancies and 15% of all hematologic malignancies. There is a monoclonal proliferation of abnormal plasma cells in this disease that results from a single malignant precursor that has undergone an uncontrolled mitotic division. Later, these cells produce one type of immunoglobulin light chain, either kappa or lambda. We present a case of a 46‑year‑old male patient who presented with a swelling of the mandible. The punched-out radiolucencies in the skull radiograph and the immunohistochemistry confirmed the case as MM.
多发性骨髓瘤（MM）是一种起源于浆细胞的恶性肿瘤。它通常在骨骼内多中心起源。它约占所有恶性肿瘤的1%，占所有血液系统恶性肿瘤的15%。在这种疾病中，异常浆细胞呈单克隆增殖，这是由单个经历了不受控制的有丝分裂的恶性前体细胞导致的。随后，这些细胞产生一种免疫球蛋白轻链，要么是κ链，要么是λ链。我们报告一例46岁男性患者，该患者表现为下颌骨肿胀。颅骨X线片上的圆形透亮区及免疫组化检查确诊该病例为多发性骨髓瘤。
