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口腔颌面部浆细胞瘤:13例临床病理研究

Plasmacytoma of the oral cavity and jaws: a clinicopathologic study of 13 cases.

作者信息

Pisano J J, Coupland R, Chen S Y, Miller A S

机构信息

Conemaugh Valley Hospital, Johnstown, Pa., USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Feb;83(2):265-71. doi: 10.1016/s1079-2104(97)90015-9.

DOI:10.1016/s1079-2104(97)90015-9
PMID:9117760
Abstract

Plasmacytoma of the jaw bones and oral cavity, as in other anatomic sites, comprises three distinct entities: multiple myeloma, solitary plasmacytoma of bone, and extramedullary plasmacytoma. This article is a retrospective study of 13 cases; 9 occurred in the mandible and 4 in the maxilla. The most common radiographic finding was a radiolucency that many times was superimposed on the roots or apices of nearby teeth. The most common symptom was localized pain, and the most frequent clinical sign was a raised red lesion on the alveolar ridge. The disease affects older persons, and the posterior mandible is the most frequently reported location. The degree of dysplasia of tumor cells was evaluated as there is a reported correlation with survival rates.

摘要

颌骨和口腔的浆细胞瘤,与其他解剖部位的情况一样,包括三种不同的实体:多发性骨髓瘤、骨孤立性浆细胞瘤和髓外浆细胞瘤。本文是一项对13例病例的回顾性研究;9例发生在下颌骨,4例发生在上颌骨。最常见的影像学表现是透射区,很多时候该透射区叠加在邻近牙齿的牙根或根尖部位。最常见的症状是局部疼痛,最常见的临床体征是牙槽嵴上隆起的红色病变。该疾病好发于老年人,下颌骨后部是最常报道的发病部位。由于据报道肿瘤细胞的发育异常程度与生存率相关,因此对其进行了评估。

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