Luxenberg J S, Plato C C, Fox K M, Friedland R P, Rapoport S I
Laboratory of Neurosciences, National Institute on Aging, Bethesda, Maryland 20892.
Am J Med Genet. 1988 Jul;30(3):733-40. doi: 10.1002/ajmg.1320300306.
Digital and palmar dermatoglyphics were examined in 29 men and 27 women with dementia of the Alzheimer type (DAT) and 112 age-, sex-, and racial group-matched controls. Female patients had significantly (p less than 0.05) more accessory triradii and complete Sydney creases than controls; no dermatoglyphic differences were detected in the males. Separating the patients by age of onset prior to or after age 65 years did not help differentiate patients from controls by dermatoglyphic profile. This study failed to confirm either the previously reported dermatoglyphic differences between DAT patients and controls or the reported similarity of the dermatoglyphic pattern of DAT to that of Down syndrome patients.
对29名患有阿尔茨海默型痴呆（DAT）的男性和27名患有阿尔茨海默型痴呆的女性以及112名年龄、性别和种族匹配的对照组进行了数字和手掌皮纹检查。女性患者的副三叉点和完整的悉尼褶痕明显（p小于0.05）多于对照组；在男性中未检测到皮纹差异。按65岁之前或之后的发病年龄对患者进行分组，无助于通过皮纹特征将患者与对照组区分开来。这项研究未能证实先前报道的DAT患者与对照组之间的皮纹差异，也未能证实所报道的DAT皮纹模式与唐氏综合征患者的皮纹模式相似。
