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LIAC术中放射治疗加速器产生的电子束的蒙特卡罗模拟

Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator.

作者信息

Robatjazi M, Tanha K, Mahdavi S R, Baghani H R, Mirzaei H R, Mousavi M, Nafissi N, Akbari E

机构信息

Medical Physics and Radiological Sciences Department, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran.

出版信息

J Biomed Phys Eng. 2018 Mar 1;8(1):43-52. eCollection 2018 Mar.

Abstract

BACKGROUND

One of the main problems of dedicated IORT accelerators is to determine dosimetric characteristics of the electron beams. Monte Carlo simulation of IORT accelerator head and produced beam will be useful to improve the accuracy of beam dosimetry.

MATERIALS AND METHODS

Liac accelerator head was modeled using the BEAMnrcMonte Carlo simulation system. Phase-space files were generated at the bottom of the applicators. These phase-space files were used as an input source in DOSXYZnrc and BEAMDP codes for dose calculation and analysis of the characteristic of the electron beams in all applicators and energies.

RESULTS

The results of Monte Carlo calculations are in very close agreement with the measurements. There is a decrease in the peak of the initial spectrum when electrons come from the end of accelerator wave guide to the end of applicator. By decreasing the applicator diameter, the mean energy of electron beam decreased. Using applicators and increasing their size, X-ray contamination will increase. The percentage of X-ray contamination increases by applicator diameter. This is related to the increase of the mean energy of electron beams.

CONCLUSION

Application of PMMA collimator leads to, although well below accepted level, the production of bremsstrahlung. The results of this study showed that special design of LIAC head accompanying by PMMA collimator system cause to produce an electron beam with an individual dosimetric characteristic making it a useful tool for intraoperative radiotherapy purposes.

摘要

背景

专用术中放疗加速器的主要问题之一是确定电子束的剂量学特征。对术中放疗加速器机头及产生的射束进行蒙特卡罗模拟,将有助于提高射束剂量测定的准确性。

材料与方法

使用BEAMnrc蒙特卡罗模拟系统对Liac加速器机头进行建模。在施源器底部生成相空间文件。这些相空间文件用作DOSXYZnrc和BEAMDP代码的输入源,用于计算所有施源器和能量下电子束的剂量并分析其特性。

结果

蒙特卡罗计算结果与测量结果非常吻合。当电子从加速器波导末端传输到施源器末端时,初始能谱峰值会降低。减小施源器直径,电子束的平均能量会降低。使用施源器并增大其尺寸,X射线污染会增加。X射线污染百分比随施源器直径增加。这与电子束平均能量的增加有关。

结论

聚甲基丙烯酸甲酯准直器的应用会导致产生轫致辐射,尽管其水平远低于可接受水平。本研究结果表明,Liac机头的特殊设计与聚甲基丙烯酸甲酯准直器系统相结合,会产生具有独特剂量学特征的电子束,使其成为术中放疗的有用工具。

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