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[肾血管性高血压的治疗:血管成形术与手术对比]

[Treatment of renovascular arterial hypertension: angioplasty versus surgery].

作者信息

Gosse P, Choussat A, Tap R, Baudet E, Fontan F, Dallocchio M

机构信息

Hôpital cardiologique, CHRU de Bordeaux, France.

出版信息

Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:213-6.

PMID:2973298
Abstract

Percutaneous transluminal angioplasty is being more and more performed as the first choice treatment of renovascular hypertension. However, very few studies are devoted to the comparison of angioplasty versus surgery in treating renovascular hypertension and no one is prospective. A group of 25 patients with renovascular hypertension who underwent surgical treatment in the years 78-82 was compared to a group of 32 patients who underwent transluminal angioplasty in the years 82-86. Age, sex, etiology and severity of the arterial stenosis, blood pressure before treatment were similar in both groups. Average follow up was 44 +/- 33 months in the surgical group (S), 18 +/- 15 months in the angioplasty group (A). In the surgical group, we noticed one death, 20 p. 100 of major complications (thrombosis or stenosis of bypass grafts). In the angioplasty group, there was no death, 82 p. 100 of initial success, 12 p. 100 of major complications which needed surgery, 22 p. 100 of restenosis which were treated with a second angioplasty. Patients were classified as cured (BP less than 140/90 without treatment and perfect renal vascularisation) improved (BP less than 160/100 without treatment or with treatment if reduced and renal artery stenosis less than 50 p. 100), unchanged (BP greater than 160/100 and/or renal artery stenosis greater than 50 p. 100 or thrombosis). (Table: see text). Results are similar in both groups. The simplicity of the procedure, a lower cost and the absence of lethal complications are in favour of the transluminal angioplasty as the first choice treatment of renovascular hypertension.

摘要

经皮腔内血管成形术正越来越多地被用作肾血管性高血压的首选治疗方法。然而,很少有研究致力于比较血管成形术与手术治疗肾血管性高血压的效果,而且没有一项是前瞻性研究。将1978 - 1982年间接受手术治疗的25例肾血管性高血压患者与1982 - 1986年间接受经皮腔内血管成形术的32例患者进行了比较。两组患者的年龄、性别、动脉狭窄的病因和严重程度、治疗前血压相似。手术组(S)的平均随访时间为44±33个月,血管成形术组(A)为18±15个月。手术组有1例死亡,20%发生主要并发症(旁路移植血管血栓形成或狭窄)。血管成形术组无死亡病例,初始成功率为82%,12%的患者发生需要手术治疗的主要并发症,22%的患者发生再狭窄并接受了二次血管成形术治疗。患者被分为治愈(未经治疗血压低于140/90且肾血管完全通畅)、改善(未经治疗血压低于160/100或治疗后血压降低且肾动脉狭窄小于50%)、未改变(血压高于160/100和/或肾动脉狭窄大于50%或血栓形成)(见表文)。两组结果相似。该手术操作简单、成本较低且无致命并发症,这使得经皮腔内血管成形术成为肾血管性高血压的首选治疗方法。

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1
[Treatment of renovascular arterial hypertension: angioplasty versus surgery].[肾血管性高血压的治疗:血管成形术与手术对比]
Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:213-6.
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[Clinical results of angioplasty of the renal arteries in renovascular arterial hypertension. A retrospective study in 113 patients].[肾血管性高血压患者肾动脉血管成形术的临床结果。对113例患者的回顾性研究]
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