Hinojosa Carlos A, Boyer-Duck Estefanía, Anaya-Ayala Javier E, Núñez-Salgado Ana E, Laparra-Escareno Hugo, Lizola René
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección de Cirugía, Sección de Angiología y Cirugía Vascular. Ciudad de México, México.
Gac Med Mex. 2018;154(2):190-197. doi: 10.24875/GMM.18002772.
Diabetic foot is a common cause of hospitalization.
To examine the impact of revascularization on lower limb salvage.
Retrospective study of diabetic patients with foot ulcers. The extent of tissue loss was assessed according to the PEDIS and Wagner classifications, and revascularization indications and techniques were evaluated. Factors involved with major amputation and limb salvage were assessed with Fisher's and chi-square tests.
A total of 307 patients with a mean age of 61 years were included in the study; 198 (64%) were males; 53 (17%) underwent limb revascularization, 26 (8%) with endovascular techniques and 27 (9%) with open surgery; 27 belonged to PEDIS grade 3 (51%) and 21 (41%) to Wagner's classification grade 4; 52% of revascularized patients required major amputation versus 25% of those without revascularization. Comorbidities, demographic variables, complications and mortality showed no differences when patients who required major amputation were compared with those who didn't.
Despite revascularization, the limb was preserved in less than 50% of patients. Early referral to vascular surgery and appropriate patient-selection criteria might increase limb salvage.
糖尿病足是住院治疗的常见病因。
研究血管重建术对下肢保肢的影响。
对患有足部溃疡的糖尿病患者进行回顾性研究。根据PEDIS和瓦格纳分类法评估组织缺失程度,并评估血管重建的指征和技术。采用Fisher检验和卡方检验评估与大截肢和保肢相关的因素。
本研究共纳入307例患者,平均年龄61岁;其中198例(64%)为男性;53例(17%)接受了肢体血管重建术,26例(8%)采用血管腔内技术,27例(9%)采用开放手术;27例属于PEDIS 3级(51%),21例(41%)属于瓦格纳分类4级;接受血管重建术的患者中有52%需要进行大截肢,而未接受血管重建术的患者中这一比例为25%。在比较需要进行大截肢的患者和不需要进行大截肢的患者时,合并症、人口统计学变量、并发症和死亡率均无差异。
尽管进行了血管重建术,但仍有不到50%的患者保住了肢体。早期转诊至血管外科并采用适当的患者选择标准可能会提高保肢率。