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肺的扫描电子显微镜放射自显影术

Scanning electron microscopic autoradiography of lung.

作者信息

Lauhala K E, Sanders C L, McDonald K E

机构信息

Biology and Chemistry Department, Pacific Northwest Laboratory, Richland, Washington 99352.

出版信息

Scanning Microsc. 1988 Sep;2(3):1631-4.

PMID:2974177
Abstract

Scanning electron microscopic (SEM) autoradiography of the lung is being used to determine the distribution of inhaled, alpha particle-emitting, plutonium dioxide particles. SEM autoradiography provides high visual impact views of alpha activity. Particles irradiating the bronchiolar epithelium were detected both on the bronchiolar surface and in peribronchiolar alveoli. The technique is being used to obtain quantitative data on the clearance rates of plutonium particles from bronchi and bronchioles.

摘要

肺部的扫描电子显微镜(SEM)放射自显影术正用于确定吸入的、发射α粒子的二氧化钚颗粒的分布情况。SEM放射自显影术能提供α活性的高视觉冲击力图像。在细支气管表面和细支气管周围的肺泡中都检测到了照射细支气管上皮的颗粒。该技术正用于获取有关钚颗粒从支气管和细支气管清除率的定量数据。

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