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宫颈癌诊断时晚期的时间趋势及相关因素:对巴西2000 - 2012年基于医院癌症登记处数据的分析

Temporal trend and associated factors to advanced stage at diagnosis of cervical cancer: analysis of data from hospital based cancer registries in Brazil, 2000-2012.

作者信息

Renna Junior Nelson Luiz, Silva Gulnar Azevedo E

机构信息

Instituto de Medicina Social, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

出版信息

Epidemiol Serv Saude. 2018;27(2):e2017285. doi: 10.5123/s1679-49742018000200003. Epub 2018 May 7.

Abstract

OBJECTIVE

To analyze the time trend and analyze the determinants of stage at diagnosis of cervical cancer in Brazil.

METHODS

Time trend analysis and cross-sectional study using data from hospital-based cancer registries (2000-2012); multinomial and joinpoint regression statistical models were used.

RESULTS

65.843 cases were analyzed; the median interval between diagnosis and treatment was 59 days; the percentage of advanced staging increased, annual percent change 1.10% (95%CI 0.80;1.50); women with higher education (compared to unlettered) had less odds of late stage diagnosis (OR=0.38; 95%CI 0.31;0.47); among indigenous (OR=2.38; 95%CI 1.06;5.33) and black women (OR=1.16; 95%CI 1.02;1.31), compared to white, and in the North region (OR=2.55; 95%CI 2.26;2.89), compared to the Southeast, the odds was higher; other factors positively related to advanced stage were 'age', 'histology', and marital status'. Conclusion Inequities affect the odds of late stage diagnosis of cervical cancer.

摘要

目的

分析巴西宫颈癌诊断分期的时间趋势并确定其影响因素。

方法

利用基于医院的癌症登记数据(2000 - 2012年)进行时间趋势分析和横断面研究;采用多项和连接点回归统计模型。

结果

共分析65843例病例;诊断与治疗的中位间隔时间为59天;晚期分期的比例上升,年变化率为1.10%(95%可信区间0.80;1.50);受过高等教育的女性(与未受过教育的女性相比)晚期诊断的几率较低(比值比=0.38;95%可信区间0.31;0.47);与白人女性相比,土著女性(比值比=2.38;95%可信区间1.06;5.33)和黑人女性(比值比=1.16;95%可信区间1.02;1.31),以及与东南部地区相比,北部地区(比值比=2.55;95%可信区间2.26;2.89)晚期诊断的几率较高;与晚期相关的其他因素包括“年龄”、“组织学”和婚姻状况。结论:不公平现象影响宫颈癌晚期诊断的几率。

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