移动医疗技术支持的家庭干预治疗成人肺移植候选者衰弱：一项试点研究。
A mobile health technology enabled home-based intervention to treat frailty in adult lung transplant candidates: A pilot study.
机构信息
Department of Medicine, University of California, San Francisco, CA, USA.
Aidcube™, San Francisco, CA, USA.
出版信息
Clin Transplant. 2018 Jun;32(6):e13274. doi: 10.1111/ctr.13274. Epub 2018 Jun 20.
BACKGROUND
Frailty is prevalent in lung transplant candidates (LTC) and is associated with waitlist delisting or death. We performed a pilot study to assess the safety and feasibility of a home-based, mobile health technology-facilitated intervention to treat frailty in LTC.
METHODS
We performed an 8-week, nonrandomized, home-based exercise and nutrition intervention in LTC with Short Physical Performance Battery (SPPB) frailty scores of ≤11. The intervention utilized a customized, mobile device application ("app") enabling monitoring and progression of the intervention in real time. We aimed to evaluate key process measures. Secondarily, we tested whether the intervention could improve frailty scores quantified by the SPPB and Fried Frailty Phenotype (FFP).
RESULTS
A total of 15 subjects enrolled were 63 ± 5.7 years old; oxygen requirements ranged from 3 to 15LPM. Thirteen subjects completed the intervention. Over 108 subject-weeks, there were no adverse events. Subjects found the app engaging and easy to work with. SPPB frailty improved in 7 (54%) and FFP improved in 8 (62%). There was a strong trend toward improved frailty scores (SPPB change 1.0 ± 1.9; P = .08; FFP change -0.6 ± 1.0; P = .07).
CONCLUSION
In this pilot study, we found that a home-based prehabilitation program that leverages mobile health technology to target frailty in LTC is well received, safe, and capable of improving physical frailty scores.
背景
衰弱在肺移植候选者（LTC）中很普遍，与等待名单除名或死亡有关。我们进行了一项试点研究，以评估一种基于家庭的、移动健康技术辅助干预措施治疗 LTC 衰弱的安全性和可行性。
方法
我们对 SPPB 衰弱评分≤11 的 LTC 患者进行了为期 8 周的非随机、基于家庭的运动和营养干预。该干预措施利用了一个定制的移动设备应用程序（“应用程序”），能够实时监测和跟踪干预措施的进展。我们旨在评估关键过程措施。其次，我们测试了该干预措施是否可以改善 SPPB 和 Fried 衰弱表型（FFP）量化的衰弱评分。
结果
共有 15 名受试者入组，平均年龄为 63±5.7 岁；氧气需求范围为 3 至 15LPM。13 名受试者完成了干预。在 108 个受试者周中，没有不良事件发生。受试者认为该应用程序具有吸引力，易于使用。SPPB 衰弱评分在 7 名（54%）受试者中得到改善，FFP 评分在 8 名（62%）受试者中得到改善。衰弱评分改善有显著趋势（SPPB 变化 1.0±1.9；P=0.08；FFP 变化 -0.6±1.0；P=0.07）。
结论
在这项试点研究中，我们发现，利用移动健康技术针对 LTC 衰弱的基于家庭的康复计划受到欢迎、安全且能够改善身体衰弱评分。
Zotero 插件