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左肾细胞癌合并IV级静脉瘤栓及严重冠状动脉狭窄的一期手术治疗罕见病例报告

A rare case report of one stage surgical treatment for left renal cell carcinoma with level IV intravenous tumor thrombus combined with severe coronary artery stenosis.

作者信息

Wang Zhenqing, Zhang Keqin, Zhang Hui, Sun Dingqi, Li Yong, Tan Qi, Fu Qiang

机构信息

Department of Urology Department of Cardiac Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

出版信息

Medicine (Baltimore). 2018 May;97(19):e0433. doi: 10.1097/MD.0000000000010433.

Abstract

RATIONALE

Renal cell carcinoma (RCC) exhibits a natural tendency to extend from the kidney into inferior vena cava (IVC) and growing into the right atrium is a rare complication. We report a 65-year-old patient with an RCC with intravascular extension through renal vein into the IVC and right atrial combined with severe coronary artery disease. This case has not been described in the literature and there is no treatment guideline for it.

PATIENT CONCERNS

A 65-year-old patient was admitted to our clinic with complaints of edema of both lower extremities.

DIAGNOSES

On the basis of the magnetic resonance imaging scan and coronary angiography, we strongly suspected an RCC with intravascular extension through renal vein into the IVC and right atrial combined with severe coronary artery disease.

INTERVENTIONS

We performed open left radical nephrectomy, IVC, and right atrium thrombectomy under cardiopulmonary bypass and coronary artery bypass grafting on beating heart.

OUTCOMES

The postoperative course was uneventful. The patient has been discharged from hospital.

LESSONS

Coexistence of severe coronary artery disease and RCC infiltrating inferior vena cava and right atrium rendered this operation as very high-risk procedure. We hope that our operational manners can prove the possibility of simultaneous difficult cardiac and urologic operation. The basic point of our report concerns the fact that the oncologic treatment was not delayed despite severe heart disease.

摘要

原理

肾细胞癌(RCC)具有自然地从肾脏延伸至下腔静脉(IVC)的倾向,而生长进入右心房是一种罕见的并发症。我们报告一名65岁的肾细胞癌患者,其肿瘤通过肾静脉发生血管内延伸至下腔静脉并累及右心房,同时合并严重冠状动脉疾病。该病例在文献中未见描述,也没有针对其的治疗指南。

患者情况

一名65岁患者因双下肢水肿主诉入院。

诊断

基于磁共振成像扫描和冠状动脉造影,我们强烈怀疑是肾细胞癌伴通过肾静脉的血管内延伸至下腔静脉和右心房,同时合并严重冠状动脉疾病。

干预措施

我们在体外循环下进行了开放性左肾癌根治术、下腔静脉及右心房血栓切除术,并在心脏跳动下进行冠状动脉搭桥术。

结果

术后过程顺利。患者已出院。

经验教训

严重冠状动脉疾病与肾细胞癌浸润下腔静脉和右心房并存使该手术成为高风险手术。我们希望我们的手术方式能够证明同时进行复杂心脏和泌尿外科手术的可能性。我们报告的重点在于尽管存在严重心脏病,但肿瘤治疗并未延迟这一事实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79bb/5959390/cc1617c71c87/medi-97-e0433-g001.jpg

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