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可回收支架治疗布加综合征合并下腔静脉血栓形成的长期疗效。

Long-term Outcome of Recoverable stents for Budd-Chiari syndrome Complicated with Inferior Vena Cava Thrombosis.

机构信息

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Department of Ultrasound, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.

出版信息

Sci Rep. 2018 May 9;8(1):7393. doi: 10.1038/s41598-018-25876-w.

DOI:10.1038/s41598-018-25876-w
PMID:29743653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5943331/
Abstract

This study aimed to present long-term results of a 12-year patient follow-up of recoverable stents for BCS complicated by inferior vena cava (IVC) thrombosis. Forty consecutive patients with BCS complicated by IVC thrombosis were treated with recoverable stents. The median duration of symptoms was 24 months. Recoverable stents was placed after predilation of the obstructed IVC, and then agitation thrombolysis or catheter-directed thrombolysis of IVC was performed. The recoverable stents was removed eventually after thrombus disappeared. Clinical patency was defined as absence or improvement of symptoms. Patients were subsequently followed-up by color Doppler ultrasound. Recoverable stents placement, balloon angioplasty and thrombolysis were technically successful in all patients. Stents were successfully removed in 92.1% of patients. A few serious related complications including one acute pulmonary thromboembolism, one stent migration, and one failure retrieval stents occurred. The median follow-up was 43.7 months. The long-term results were satisfactory except 2 patients who presented with a restenosis or re-obstruction and underwent additional therapy. There were 5 deaths owing to pulmonary embolism or underlying malignant disease 0.4-101.8 months after the procedures, including one procedure-related death. In conclusion, Recoverable stents treatment is safe and effective for BCS complicated by IVC thrombosis, with a good long-term outcome.

摘要

本研究旨在报告可回收支架治疗布加综合征(BCS)合并下腔静脉(IVC)血栓形成的 12 年患者随访的长期结果。40 例 BCS 合并 IVC 血栓形成的连续患者接受了可回收支架治疗。症状的中位持续时间为 24 个月。在阻塞的 IVC 预扩张后放置可回收支架,然后进行 IVC 搅拌溶栓或导管定向溶栓。血栓消失后最终取出可回收支架。临床通畅性定义为症状的缺失或改善。随后通过彩色多普勒超声对患者进行随访。所有患者的可回收支架置入、球囊血管成形术和溶栓均获得技术成功。92.1%的患者成功取出支架。少数严重相关并发症包括 1 例急性肺血栓栓塞、1 例支架移位和 1 例支架取出失败。中位随访时间为 43.7 个月。除 2 例出现再狭窄或再阻塞并接受额外治疗的患者外,长期结果令人满意。5 例患者在手术后 0.4-101.8 个月因肺栓塞或基础恶性疾病死亡,其中 1 例与手术相关。总之,可回收支架治疗 BCS 合并 IVC 血栓形成是安全有效的,具有良好的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/93ca5f34581a/41598_2018_25876_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/6edf608f3183/41598_2018_25876_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/ae1f84f870f6/41598_2018_25876_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/85213e2a4252/41598_2018_25876_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/85955e9862f2/41598_2018_25876_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/93ca5f34581a/41598_2018_25876_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/6edf608f3183/41598_2018_25876_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/ae1f84f870f6/41598_2018_25876_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/85213e2a4252/41598_2018_25876_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/85955e9862f2/41598_2018_25876_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7759/5943331/93ca5f34581a/41598_2018_25876_Fig5_HTML.jpg

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