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经股静脉途径失败后建立颈静脉-股静脉途径对布加综合征复杂下腔静脉再通。

Establishing a jugular-femoral venous route for recanalization of complicated inferior vena cava in Budd-Chiari Syndrome after transfemoral access failure.

机构信息

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No.1, East Jian She Road, Zhengzhou, 450052, China.

出版信息

Sci Rep. 2022 Mar 10;12(1):3903. doi: 10.1038/s41598-022-07935-5.

Abstract

Recanalization of inferior vena cava (IVC) with complete obstruction, old thrombosis or long segmental stenosis/obstruction (complicated IVC) via transfemoral access may fail in patients with Budd-Chiari syndrome (BCS). In this study, 34 consecutive patients with BCS underwent recanalization of complicated IVC occlusion via jugular-femoral venous (JFV) route establishment. BCS with complicated IVC was detected by reviewing preoperative color Doppler ultrasonography or computed tomography (CT) venography, and confirmed by intraoperative venography. Clinical data on technical success, complications, and follow-up outcomes were analyzed. Except for one patient received surgical repair of rupture IVC after recanalization, technical success of IVC recanalization was achieved in remaining 33 (97.1%) patients. No perioperative deaths was found. Three complications were observed during recanalization, for a complication rate of 8.8%. Bleeding of the femoral vein was observed in one patient, and two patients showed bleeding of IVC. The IVC lesion diameter and blood flow of the distal IVC increased significantly after the procedure. Twenty-four patients (77.4%) were clinically cured, and four patients (12.9%) showed clinical improvement. The 1-year, 3-year, 5-year primary patency rates were 85.9%, 76.4% and 70.0%, respectively. The 5-year secondary patency rate was 96.8%. There were three deaths during follow up, and the 5-year survival rate was 90.0%. In conclusion, JFV route establishment and angioplasty for complicated IVC is safe and effective for patients with BCS after transfemoral access failure.

摘要

下腔静脉(IVC)完全阻塞、陈旧性血栓或长节段狭窄/阻塞(复杂 IVC)经股静脉途径再通可能会在布加综合征(BCS)患者中失败。本研究中,34 例 BCS 患者通过颈静脉-股静脉(JFV)途径建立来进行复杂 IVC 闭塞再通。BCS 合并复杂 IVC 通过术前彩色多普勒超声或计算机断层扫描(CT)静脉造影检查发现,并通过术中静脉造影证实。分析了技术成功率、并发症和随访结果的临床数据。除了 1 例患者在再通后接受了破裂 IVC 的手术修复外,其余 33 例(97.1%)患者 IVC 再通均获得技术成功。无围手术期死亡。在再通过程中观察到 3 种并发症,并发症发生率为 8.8%。1 例患者出现股静脉出血,2 例患者出现 IVC 出血。术后 IVC 病变直径和远端 IVC 血流明显增加。24 例(77.4%)患者临床治愈,4 例(12.9%)患者临床症状改善。1 年、3 年和 5 年的原发性通畅率分别为 85.9%、76.4%和 70.0%,5 年的继发性通畅率为 96.8%。随访期间死亡 3 例,5 年生存率为 90.0%。总之,对于经股静脉途径失败的 BCS 患者,JFV 途径建立和血管成形术治疗复杂 IVC 是安全有效的。

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