戈谢病与慢性髓性白血病：首例同时接受酶替代疗法和酪氨酸激酶抑制剂治疗的患者报道。
Gaucher disease and chronic myeloid leukemia: first reported patient receiving enzyme replacement and tyrosine kinase inhibitor therapies simultaneously.
作者信息
Noya MSoledad, Andrade-Campos Marcio, Irun Pilar, López de Frutos Laura, López-Fernandez MFernanda, Giraldo Pilar
机构信息
Department of Hematology CHUAC A Coruña Spain.
Translational Research Unit Miguel Servet University Hospital IIS-Aragon Zaragoza Spain.
出版信息
Clin Case Rep. 2018 Mar 15;6(5):887-892. doi: 10.1002/ccr3.1460. eCollection 2018 May.
Abstract
Report a female diagnosed as type 1 Gaucher disease after a femoral pathologic fracture when she was 55 years old. Enzyme replacement therapy was started, and she achieved therapeutic goals. In 2015, a Ph' CML with numerous pseudo-Gaucher cells in bone marrow appears. BCR/ABL was not present at GD diagnosis.
摘要
报告一名55岁女性，因股骨病理性骨折被诊断为1型戈谢病。开始进行酶替代治疗后，她达到了治疗目标。2015年，出现了骨髓中有大量假戈谢细胞的Ph' 慢性粒细胞白血病。在戈谢病诊断时未检测到BCR/ABL。
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