使用离子液体激活脂肪酶催化反应用于有机合成。

Activation of Lipase-Catalyzed Reactions Using Ionic Liquids for Organic Synthesis.

作者信息

Itoh Toshiyuki

机构信息

Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori, Japan.

Center for Research on Green Sustainable Chemistry, Tottori University, Tottori, Japan.

出版信息

Adv Biochem Eng Biotechnol. 2019;168:79-104. doi: 10.1007/10_2018_62.

DOI:10.1007/10_2018_62

PMID:29744541

Abstract

The use of ionic liquids to replace organic or aqueous solvents in biocatalysis processes has recently received great attention, and much progress has been made in this area; the lipase-catalyzed reactions are the most successful. Recent developments in the application of ionic liquids as solvents in lipase-catalyzed reactions for organic synthesis are reviewed, focusing on the ionic liquid mediated activation method of lipase-catalyzed reactions.

摘要

近年来，在生物催化过程中使用离子液体替代有机或水性溶剂备受关注，并且在该领域已取得了很大进展；其中脂肪酶催化反应最为成功。本文综述了离子液体作为溶剂在脂肪酶催化有机合成反应中的应用进展，重点关注离子液体介导的脂肪酶催化反应活化方法。