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非典型细胞性神经鞘黏液瘤:皮肤良性和恶性梭形细胞病变的潜在诊断陷阱。

Atypical cellular neurothekeoma: A potential diagnostic pitfall for benign and malignant spindle cell lesions in skin.

作者信息

Tran Patrick, McLemore Michael

机构信息

David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

出版信息

J Cutan Pathol. 2018 Aug;45(8):619-622. doi: 10.1111/cup.13274. Epub 2018 Jun 12.

DOI:10.1111/cup.13274
PMID:29744902
Abstract

Cellular neurothekeomas (CNTs) are rare, benign cutaneous tumors that arise primarily on the head and neck, with a slight female predominance. CNTs with atypical features have been described, including those with an infiltrative growth pattern. Although CNTs with atypical features are benign, recognition of this entity can pose diagnostic challenges. Here, we report a case of CNT with an unusual clinical presentation on the left second digit, and with atypical histological features including an infiltrative growth pattern, which could have been mistaken for features of malignancy.

摘要

细胞性神经鞘瘤(CNTs)是一种罕见的良性皮肤肿瘤,主要发生在头颈部,女性略占优势。已描述了具有非典型特征的CNTs,包括那些具有浸润性生长模式的肿瘤。尽管具有非典型特征的CNTs是良性的,但识别这一实体可能会带来诊断挑战。在此,我们报告一例发生于左手第二指、临床表现不寻常且具有包括浸润性生长模式在内的非典型组织学特征的CNT病例,这些特征可能会被误诊为恶性特征。

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