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老年非典型性细胞神经鞘瘤(ACN):病例报告及文献复习。

Atypical cellular neurothekeoma (ACN) of the elderly: case report and brief review of the literature.

机构信息

Department of Radiological, Oncological and Pathological Sciences, Sapienza, University of Rome, Rome, Italy.

Department of General Surgery and Surgical Specialties "P. Stefanini", Sapienza University of Rome, Rome, Italy.

出版信息

Pathologica. 2020 Dec;112(4):210-213. doi: 10.32074/1591-951X-104.

DOI:10.32074/1591-951X-104
PMID:33393524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8183354/
Abstract

Atypical cellular neurothekeoma (ACN) is an aggressive and rare variant of cellular neurothekeoma. Only few cases have been reported in the literature and the biological behavior seems to be uncertain. We describe the case of an ACN presenting on the scalp of an elderly man, emphasizing the cytologic features of malignancy. In addition, we provide a brief overview of the literature and discuss the differential diagnosis with other entities, and the possible diagnostic pitfalls.

摘要

非典型细胞神经鞘瘤(ACN)是细胞神经鞘瘤的一种侵袭性罕见变体。文献中仅报道了少数病例,其生物学行为似乎不确定。我们描述了一例发生于老年男性头皮的 ACN 病例,强调了其恶性细胞学特征。此外,我们还简要概述了文献,并讨论了与其他实体的鉴别诊断以及可能的诊断陷阱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/c135f7c768d3/pathol-2020-04-210-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/a8b86560166f/pathol-2020-04-210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/cd3cc69e6c08/pathol-2020-04-210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/4b35d9e49e9e/pathol-2020-04-210-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/ee28929912ed/pathol-2020-04-210-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/c135f7c768d3/pathol-2020-04-210-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/a8b86560166f/pathol-2020-04-210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/cd3cc69e6c08/pathol-2020-04-210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/4b35d9e49e9e/pathol-2020-04-210-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/ee28929912ed/pathol-2020-04-210-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef71/8183354/c135f7c768d3/pathol-2020-04-210-g005.jpg

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本文引用的文献

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Multiple cellular neurothekeomas in a middle-aged woman including the lower extremity: A case report and review of the current literature.一名中年女性包括下肢的多发性细胞性神经鞘黏液瘤:病例报告及当前文献综述
J Cutan Pathol. 2019 Jan;46(1):67-73. doi: 10.1111/cup.13366. Epub 2018 Nov 8.
2
Atypical cellular neurothekeoma: A potential diagnostic pitfall for benign and malignant spindle cell lesions in skin.非典型细胞性神经鞘黏液瘤:皮肤良性和恶性梭形细胞病变的潜在诊断陷阱。
J Cutan Pathol. 2018 Aug;45(8):619-622. doi: 10.1111/cup.13274. Epub 2018 Jun 12.
3
High prevalence of MiTF staining in undifferentiated pleomorphic sarcoma: caution in the use of melanocytic markers in sarcoma.
在未分化多形性肉瘤中 MiTF 染色的高发生率:在肉瘤中使用黑色素细胞标志物时要谨慎。
Histopathology. 2017 Apr;70(5):734-745. doi: 10.1111/his.13139. Epub 2017 Feb 1.
4
Cellular neurothekeoma: analysis of 37 cases emphasizing atypical histologic features.细胞神经鞘瘤:37 例强调非典型组织学特征的分析。
Mod Pathol. 2014 May;27(5):701-10. doi: 10.1038/modpathol.2013.190. Epub 2013 Nov 1.
5
Atypical cellular neurothekeoma in a pregnant woman.一名孕妇的非典型细胞性神经鞘黏液瘤。
Arch Dermatol. 2011 Nov;147(11):1342-3. doi: 10.1001/archdermatol.2011.333.
6
Cellular neurothekeoma with neuroendocrine differentiation.具有神经内分泌分化的细胞性神经鞘黏液瘤。
Dermatol Online J. 2011 Apr 15;17(4):2.
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A rare case of atypical cellular neurothekeoma in a 68-year-old woman.一名68岁女性患非典型细胞性神经鞘黏液瘤的罕见病例。
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