Tanaka A, Fukayama M, Funata N, Koike M, Saito K
Department of Pathology, Tokyo Metropolitan Komagome Hospital, Japan.
Virchows Arch A Pathol Anat Histopathol. 1988;414(1):9-14. doi: 10.1007/BF00749732.
Two elderly males died suddenly of acute myocardial infarction. Autopsy disclosed extensive and severe coronary arteritis, associated with aortitis. In most of all of the epicardial coronary arteries, fibrous thickening of the adventitia was remarkable and muscle layers of the media were nearly destroyed by infiltration of lymphocytes and plasma cells. The aorta showed adventitial thickening with destruction of the elastic layers of the outer media. In the literature, similar extensive coronary arteritis has been reported in five cases of Takayasu's arteritis. All cases, including ours, were elderly or middle-aged males who died suddenly of myocardial infarction without the antemortem detection of the underlying arteritis. These aspects differ from the typical Takayasu's arteritis and we suggest that these cases are considered as a separate entity.
两名老年男性因急性心肌梗死突然死亡。尸检发现广泛而严重的冠状动脉炎，并伴有主动脉炎。在几乎所有的心外膜冠状动脉中，外膜纤维增厚明显，中膜肌层几乎被淋巴细胞和浆细胞浸润破坏。主动脉显示外膜增厚，外中膜弹性层破坏。文献中曾报道5例大动脉炎患者出现类似的广泛冠状动脉炎。包括我们的病例在内，所有病例均为老年或中年男性，因心肌梗死突然死亡，生前未检测到潜在的动脉炎。这些情况与典型的大动脉炎不同，我们建议将这些病例视为一个独立的实体。
